Anti-GluN2C/NR2C Antibody (N422/18)

Our mouse GluN2C/NR2C monoclonal antibody from NeuroMab is produced in-house from clone N422/18. It detects human, mouse, and rat GluN2C/NR2C and is purified by Protein A chromatography. KO validated. Works in WB, IHC, ICC, ELISA.

Immunofluorescence staining of sections from adult GluN2C/NR2C wild-type (WT) and knockout (KO) mouse cerebellum with N422/18 (GluN2C/NR2C, red) and L106/83 (Gephyrin, green) TC supe. Tissue courtesy of Sharon Swanger and Stephen Traynelis (Emory).
Adult rat brain membrane immunoblot.
Immunoblot versus crude membrane fractions from GluN2C/NR2C knockout (KO) and wild-type (WT) mouse cerebella probed with N422/18 (top) and tubulin (bottom). Data courtesy of Bo-Shiun Chen (Augusta University) and reproduced with permission from Scientific Reports (2016 Chung et al, PMID 27845401).
Immunoblot from NAc synaptoneurosomal preparation of WT and GluN2C KO mice, confirming loss of GluN2C subunit. Image from publication CC-BY-4.0. PMID: 35867797
Immunofluorescence staining of sections from adult GluN2C/NR2C wild-type (WT) and knockout (KO) mouse cerebellum with N422/18 (GluN2C/NR2C, red) and L106/83 (Gephyrin, green) TC supe. Tissue courtesy of Sharon Swanger and Stephen Traynelis (Emory).
Immunofluorescence staining of sections from adult GluN2C/NR2C wild-type (WT) and knockout (KO) mouse cerebellum with N422/18 (GluN2C/NR2C, red) and L106/83 (Gephyrin, green) TC supe. Tissue courtesy of Sharon Swanger and Stephen Traynelis (Emory).
Click on image to zoom

Human, Mouse, Rat
ELISA, ICC, IHC, WB
Mouse
490
550
594
650
Biotin
Carrier-Free

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Data Sheet
KO Validated KO Validated

SKU: 75-411

Volume: 100 µL
Price:
$337.00
Ships: 1-2 business days

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