Anti-GluN1/NR1 Glutamate Receptor Antibody (N308/48)
Our mouse GluN1/NR1 glutamate receptor monoclonal antibody from NeuroMab is produced in-house from clone N308/48. It detects human, mouse, and rat GluN1/NR1 glutamate receptor and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.
Human, Mouse, Rat
ELISA, ICC, IHC, WB
Mouse
SKU: 75-272
Ships: 1-2 business days
Product Details
GluN1/NR1 glutamate receptor
Glutamate receptor 1, NMDA 1, or GluN1/NR1 also known as subunit 1 of the N-methyl-D-aspartate (NMDA) receptor. It is a member of the glutamate receptor channel superfamily and is a heteromeric glutamate-gated calcium ion channel. GluN1 is essential for synaptic function in the brain. GluN1 is expressed throughout the brain in cerebellum, thalamus, olfactory bulb and cortex in the membrane at postsynaptic density. GluN1 plays a key role in synaptogenesis, synaptic plasticity, memory acquisition and learning. Mutations in the GluN1 gene are associated with intellectual disability and cortical visual impairment and movement disorders.
Purified by Protein A chromatography
1 mg/mL
Monoclonal
N308/48
IgG1
ELISA, ICC, IHC, WB
Mouse
Grin1 Nmdar1
105 kDa
Fusion protein amino acids 42-361 (extracellular N-terminus) of rat NR1 (accession number P35439) produced recombinantly in E. Coli
Rat
Human, Mouse, Rat
AB_11000180
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
WB: 1:500
IHC: 1:500
ICC: 1:250
IHC: 1:500
ICC: 1:250
Unconjugated
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Shipped on ice packs

