Anti-GluA2/GluR2 Glutamate Receptor Antibody (BSA and Azide free) (L21/32)

Name: Anti-GluA2/GluR2 Glutamate Receptor Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-002-CF
Price: 486.0 USD
Availability: InStock

Our mouse GluA2/GluR2 glutamate receptor carrier-free monoclonal antibody from NeuroMab is produced in-house from clone L21/32. It detects human, mouse, and rat GluA2/GluR2 glutamate receptor and is purified by Protein A chromatography. KO validated. Works in WB, IHC, ICC, ELISA.

Anti-GluA2/GluR2 Glutamate Receptor Antibody (BSA and Azide free)

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

KO Validated

SKU: 75-002-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

GluA2/GluR2 glutamate receptor

Scientific Background

Glutelin type-A 2 (GluA2) , also called GRIA2, GLUR2, GLURB, GluA2, GluR-K2, HBGR2 or glutamate ionotropic receptor AMPA type subunit 2, is a member of the Glutamate receptor family of the mammalian brain. This neurotransmiter receptor subunit, which is activated during normal central nervous system fuction, is encoded by the GRIA2 (or GLUR2) gene. GluA2 constitutes a key subunit that regulates AMPA receptors. AMPA receptors lacking of Glua2 have been shown to be present in diseased brains, whose basic fuctions have been altered.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

L21/32

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Gria2 Glur2

Molecular Weight

90 kDa

Immunogen

Fusion protein amino acids 834-883 (EFCYKSRAEAKRMKVAKNPQNINPSSSQNSQNFATYKEGYNVYGIESVKI, cytoplasmic C-terminus) of rat GluA2/GluR2 produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

Does not cross-react with GluA1/GluR1, GluA3/GluR3 or GluA4/GluR4 (based on KO validation results)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2)

UniProt ID

P19491

Shipping

Shipped on ice packs

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Anti-GluA2/GluR2 Glutamate Receptor Antibody (BSA and Azide free) (L21/32)

SKU: 75-002-CF

Product Details

Bulk Order Anti-GluA2/GluR2 Glutamate Receptor Antibody (BSA and Azide free)

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