Anti-GluA1/GluR1 Glutamate Receptor Antibody FL490 Conjugate (N355/1)

Name: Anti-GluA1/GluR1 Glutamate Receptor Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-327-FL490
Price: 543.0 USD
Availability: InStock

Our mouse GluA1/GluR1 glutamate receptor FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N355/1. It detects human, mouse, and rat GluA1/GluR1 glutamate receptor and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-GluA1/GluR1 Glutamate Receptor Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-327-FL490

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

GluA1/GluR1 glutamate receptor

Scientific Background

Glutamate receptor 1 or GluA1/GluR1 glutamate receptor is a member of the glutamate-gated ion channel family. GluR1 funcitons as an excitatory neurotransmitter at many synapses in the central nervous system and is widely expressed in brain. Mutations in the GluR1 gene are associated with cerebral cortical dysplasia, Status Epilepticus, and depression.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N355/1

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Gria1 Glur1

Molecular Weight

100 kDa

Immunogen

Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1 (accession number P19490) produced recombinantly in E. Coli.

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940132

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with GluR2

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1)

UniProt ID

P19490

Shipping

Shipped on ice packs

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Anti-GluA1/GluR1 Glutamate Receptor Antibody FL490 Conjugate (N355/1)

SKU: 75-327-FL490

Product Details

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