IHC IP WB
Zinedin, Stiatin4 or Protein Phosphatase 2 Regulatory Subunit B'Gamma is encoded by the gene STRN4 and is a member of the Striatin family (which also includes Stiatin and SG2NA). Zinedin is a scaffolding protein with multiple protein binding domains. Zinedin binds calmodulin and acts as a calcium dependent signaling protein. Zinedin is found in the brain and the nervous system. Diseases associated with this gene includeing Cerebral Cavernous Malformations 3 and Muscular Dystrophy-Dystroglycanopathy.
Fusion protein amino acids 42-354 of human Zinedin/Striatin-4 (accession number Q9NRL3); Rat: 95% identity (300/313 amino acids identical); Mouse: 96% identity (300/313 amino acids identical); 52% identity with human Striatin-3
No cross-reactivity reported
TC Supernatant: AB_10671953
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.