Products: Primary Antibodies
PRODUCT OPTIONS
★ Trial Size Available ★Brand | Catalog # | Option | Volume | Concentration | Price | |
---|---|---|---|---|---|---|
Brand![]() |
Catalog # 75-066 |
Option Purified |
Volume 100 µL |
Concentration 1 mg/mL |
Price $335.00 |
|
Brand![]() |
Catalog # 75-066-020 |
Option Purified Trial-Size |
Volume 20 µL |
Concentration 1 mg/mL |
Price $119.00 |
|
Brand![]() |
Catalog # 73-066 |
Option TC Supernatant |
Volume 5 mL |
Concentration Lot dependent |
Price $335.00 |
Product Details
Monoclonal
Mouse
IgG1
Human Mouse Rat
ICC IHC WB
Vesicular glutamate transporter 1 (Vglut1) is encoded by the gene Slc17a7 and belongs to the vesicular glutamate transporter family. Vglut1 is expressed in glutamatergic neurons in brain regions including the cerebellum, cerebral cortex and hippocampus at synaptic vesicles. Isoform 2 is expressed in retinal. Vglut1 functions to uptake glutamate into synaptic vesicles in excitatory neural cells. Altered expression of Vglut1 has been implicated in several neurological and psychiatric diseases including Alzheimer’s disease, Parkinson’s disease, epilepsy and schizophrenia.
Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1 (also known as Vesicular glutamate transporter 1, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Bnpi, Solute carrier family 17 member 7 and Slc17a7, accession number Q62634); Mouse: 97% identity (66/68 amino acids identical); Human: 95% identity (65/68 amino acids identical); 50% identity with VGlut2 or VGlut3
Does not cross-react with VGlut2 or VGlut3
VGlut1
Slc17a7 Bnpi Vglut1
Purified: AB_2187693
Purified Trial-Size: AB_2187693
TC Supernatant: AB_10673111
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
52 kDa
Quality Control
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.