Anti-VAChT Antibody (N425/45)

Name: Anti-VAChT Antibody
Brand: NeuroMab
SKU: 75-429
Price: 319.0 USD
Availability: InStock

Our Anti-VAChT mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N425/45. It detects mouse and rat VAChT, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Adult rat trigeminal and facial motor nuclei immunohistochemistry.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-429

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

VAChT

Target Description

Vesicular acetylcholine transporter (VaCht), or Solute Carrier Family 18 Member A3 is encoded by the gene Slc18a3 and is a member of the vesicular amine transporter family. VaCht transports acetylcholine into secretory vesicles for release into the extracellular space. VaCht is expressed in major cholinergic cell groups in the peripheral and central cholinergic nervous systems. Diseases associated with SLC18A3 include Myasthenic Syndrome and Presynaptic and Presynaptic Congenital Myasthenic Syndromes.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N425/45

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Slc18a3 Vacht Vat

Molecular Weight

60 kDa

Antigen

Fusion protein amino acids 55-125 (first vesicle lumen domain) of rat VAChT (accession number Q62666) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2632411

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with VMAT1 or VMAT2

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Vesicular acetylcholine transporter (VAChT) (rVAT) (Solute carrier family 18 member 3)

UniProt Details

UniProt (Human): Q16572
UniProt (Immunogen Species): Q62666

Product Specific References for Applications and Species

Immunohistochemistry: Rat

Immunohistochemistry: Rat
PMID	Dilution	Publication
26644354	not listed	Gong, B., et al. 2016. Developing high-quality mouse monoclonal antibodies for neuroscience research - approaches, perspectives and opportunities. New Biotechnology, 551-564.

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Anti-VAChT Antibody (N425/45)

SKU: 75-429

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-VAChT Antibody

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