Human Mouse Rat
ICC IHC WB
ATPase Family AAA Domain-containing 1 is encoded by the gene ATAD1. ATAD1 plays a critical role in regulating the surface expression of AMPA receptors thereby regulating synaptic plasticity, learning, and memory. Diseases associated with ATAD1 include Hyperekplexia 4 and Hyperekplexia.
Fusion protein amino acids 1-361 (full-length) of mouse Thorase (also known as ATPase family AAA domain-containing protein 1 and Atad1, accession number Q9D5T0); Human: 100% identity (361/361 amino acids identical); Rat: 99% identity (360/361 amino acids identical)
No cross-reactivity reported
TC Supernatant: AB_10673514
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.