Human Mouse Rat
ICC IHC WB
Synaptotagmins are a family of calcium sensing, membrane trafficking proteins. 17 different synaptotagmins have been identified in mammals. Along with synaptotagmins 1 and 2, synaptotagmin 9 (also known as synaptotagmin 5) has been shown to function as a Ca(2+) sensor for fast synchronous neurotransmitter release (Xu J et al., 2007).
Fusion protein amino acids 253-344 (cytoplasmic C2B domain) of mouse Synaptotagmin-9 (also known as Synaptotagmin-5, Synaptotagmin V, SytV, Syt5, Synaptotagmin-IX, SytIX and Syt9, accession number Q9R0N5)
Rat: 100% identity (92/92 amino acids identical)
Human: 100% identity (92/92 amino acids identical)>50% identity with Synaptotagmin-1 (and other Synaptotagmins)
Does not cross-react with Synaptotagmin-1 (or other Synaptotagmins)
Synaptotagmin-5 (Synaptotagmin IX) (Synaptotagmin V) (SytV)
TC Supernatant: AB_2315937
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.