Anti-SNAT1 Antibody (N104/37)

Name: Anti-SNAT1 Antibody
Brand: NeuroMab
SKU: 75-155
Price: 319.0 USD
Availability: InStock

Our Anti-SNAT1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N104/37. It detects human, mouse, and rat SNAT1, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Surface expression of SNAT1 and SNAT2 in HCC1806 cells starved of amino acids over 24 h. Image from publication CC-BY-4.0. PMID:36210829

Adult rat brain membrane (RBM) immunoblot.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-155

Volume: 100 µL

Variant

Price:

$319

Quantity:

Product Details

Target

SNAT1

Target Description

Sodium-coupled neutral amino acid transporter 1 (SNAT1) or Solute Carrier Family 38 Member 1 is encoded by the gene Slc38a1 and belongs to the amino acid/polyamine transporter 2 family. SNAT1 acts as a sodium-dependent transporter of glutamine which serves as a precursor for the synaptic transmitter, glutamate. SNAT1 is expressed in brain, specifically at glutamatergic and GABAergic neurons, and also expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis. Diseases associated with this gene include Klatskin's Tumor.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N104/37

Isotype

IgG1

Applications

ICC, WB

Host Species

Mouse

Gene Name

Slc38a1 Ata1 Glnt Sa2 Sat1 Snat1

Molecular Weight

50 kDa

Antigen

Fusion protein amino acids 1-63 (cytoplasmic N-terminus) of rat SNAT1 (accession number Q9JM15) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2254872

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.81

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Sodium-coupled neutral amino acid transporter 1 (Amino acid transporter A1) (rATA1) (Glutamine transporter) (N-system amino acid transporter 2) (Solute carrier family 38 member 1) (System A amino acid transporter 1) (System A transporter 2) (System N amino acid transporter 1)

UniProt Details

UniProt (Human): Q9H2H9
UniProt (Immunogen Species): Q9JM15

Brown MN, Mathews GC. (2010), 'Activity- and age-dependent modulation of GABAergic neurotransmission by system A-mediated glutamine uptake..' Journal of Neurochemistry. 10.1111/j.1471-4159.2010.06823.x.

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Anti-SNAT1 Antibody (N104/37)

SKU: 75-155

Product Details

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