Products: Primary Antibodies

Anti-Snapin/SNAPAP Antibody (L8/15)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-045
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-045
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

IHC IP WB

Target Description:

SNARE-associated protein Snapin, SNAP Associated Protein or Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 7 (BLOC-1 Subunit 7) is encoded by the gene SNAPIN. Snapin is a member of the BLOC-1 complex, which is involved in the protein-sorting, membrane biogenesis, and vesicular trafficking. Snapin is required for vesicle docking and fusion and regulates neurotransmitter release. Snapin is expressed in many tissues including heart, brain, testis, kidney and liver. Diseases associated with this gene include Hermansky-Pudlak Syndrome and Tricuspid Valve Stenosis.

Immunogen:

Synthetic peptide of amino acids 115-136 of human snapin (KETARRRAMLDSGIYPPGSPGK; accession number Q95295); Rat: 95% identity (21/22 amino acids); Mouse: 95% identity (21/22 amino acids)

Cross Reactivity:

No cross-reactivity reported

Protein Name(s):

Snapin/SNAPAP

Gene Name(s):

SNAPIN BLOC1S7 SNAP25BP SNAPAP

Antibody Registry ID:

Purified: AB_2255078
TC Supernatant: AB_10675326


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

20 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.