Products: Primary Antibodies

Anti-SAPAP3 Antibody (L126/93)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
73-502
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00
Brand
NeuroMab Logo
Catalog #
75-502
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00

Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2b

Species Reactivity:

Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC IHC WB

Target Description:

Disks large-associated protein 3,SAP90/PSD-95-Associated Protein 3 or SAPAP3 is encoded by the gene DLGAP3 and is a member of the SAPAP or DLGAP family of proteins. SAPAP3 acts as a scaffold protein and is involved with glutamate receptor signaling. SAPAP3 is highly expressed in the central and peripheral nervous system. Within the cell, SAPAP3 is found at the postsynaptic density. Diseases associated with DLGAP3 include Trichotillomania and Body Dysmorphic Disorder.

Immunogen:

Fusion protein amino acids 790-977 (C-terminus) of mouse SAPAP3 (also known as Disks largeassociated protein 3, PSD-95/SAP90-binding protein 3, SAP90/PSD-95-associated protein 3, Dlgap3 and Dap3, accession number Q6PFD5); Rat: 100% identity (188/188 amino acids identical); Human: 99% identity (186/188 amino acids identical); >60% identity with SAPAP2/DLGAP2 and other SAPAP/DLGAP proteins

Antibody Registry ID:

TC Supernatant: AB_2756364
Purified:


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

110 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.