Products: Primary Antibodies

Anti-TRESK Antibody (N467/1)

from NeuroMab

PRODUCT OPTIONS

Brand	Catalog #	Option	Volume	Concentration	Price
Brand	Catalog # 75-475	Option Purified	Volume 100 µL	Concentration 1 mg/mL	Price $275.00
Brand	Catalog # 73-475	Option TC Supernatant	Volume 5 mL	Concentration Lot dependent	Price $275.00

"TC Supernatant" vs. "Purified"

TC Supernatant
Hybridoma tissue-culture supernatant (5mL) generally containing 10-50 ug/mL monoclonal antibody (clone-dependent) can be a very economical choice. Supernatant is suitable for most applications including Western Blot, immunocytochemistry, immunohistochemistry etc. For applications requiring higher antibody concentration or purity (such as immunoprecipitation, microinjection, or conjugation) it is recommended that you purchase the purified form of the antibody (supplied at 1mg/mL).

Purified mAbs
Produced by in vitro bioreactor culture of hybridoma lines followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody at 1mg/mL.

Validation Images

Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2b

Species Reactivity:

Mouse Rat

Applications:

IHC WB

Target Description:

Potassium two pore domain channel subfamily K member 18 is encoded by the gene KCNK18. KCNK18 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK18 is an outward rectifying potassium channel that produces rapidly activating outward rectifier K+ currents. KCNK18 is expressed in the brain, spinal cord, and testis. Diseases associated with KCNK18 include Migraine With or Without Aura 13 and Migraine with Aura.

Immunogen:

Fusion protein amino acids 185-283 (intracellular loop) of mouse TRESK (also known as Potassium channel subfamily K member 18, TWIK-related individual potassium channel, TWIK-related spinal cord potassium channel, Two-pore-domain potassium channel TRESK, Kcnk18, TRIK, Tresk-2 and Tresk2, accession number Q6VV64)

Protein Name(s):

TRESK (Potassium channel subfamily K member 18) (TWIK-related individual potassium channel) (TWIK-related spinal cord potassium channel) (Two-pore-domain potassium channel TRESK) (Kcnk180 (TRIK) (Tresk-2) (Tresk2)

Gene Name(s):

Kcnk18 Tresk-2 Tresk2

Antibody Registry ID:

Purified: AB_2744558
TC Supernatant: AB_2650451

Antibody Validation and Application Notes

This antibody has been validated using the following assays:

Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Molecular Weight:

40-50 kDa

Quality Control

The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.