Potassium two pore domain channel subfamily K member 18 is encoded by the gene KCNK18. KCNK18 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK18 is an outward rectifying potassium channel that produces rapidly activating outward rectifier K+ currents. KCNK18 is expressed in the brain, spinal cord, and testis. Diseases associated with KCNK18 include Migraine With or Without Aura 13 and Migraine with Aura.
Fusion protein amino acids 185-283 (intracellular loop) of mouse TRESK (also known as Potassium channel subfamily K member 18, TWIK-related individual potassium channel, TWIK-related spinal cord potassium channel, Two-pore-domain potassium channel TRESK, Kcnk18, TRIK, Tresk-2 and Tresk2, accession number Q6VV64)
TRESK (Potassium channel subfamily K member 18) (TWIK-related individual potassium channel) (TWIK-related spinal cord potassium channel) (Two-pore-domain potassium channel TRESK) (Kcnk180 (TRIK) (Tresk-2) (Tresk2)
Kcnk18 Tresk-2 Tresk2
TC Supernatant: AB_2650451
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.