ICC IHC WB
The REEP protein family is made up of six REEP proteins 1-6. REEP1/2 are mitochondrial proteins that link ER tubules to the cytoskeleton and are involved in ER formation and remodeling. They may play a role in the cell surface expression of odorant receptors. Expression of the REEP1/REEP2 is found in neuronal and neuronal-like exocytotic tissues.
Fusion protein amino acids 111-254 (cytoplasmic C-terminus) of mouse REEP2 (also known as Receptor expression-enhancing protein 2, C5orf19, SGC32445 and LOC682105, accession number Q8VCD6) Rat: 97% identity (140/144 amino acids identical) Human: 86% identity (125/144 amino acids identical) <40% identity with REEP1 and REEP4 but >65% identity for first 46 amino acids (RDKSYETMMRV GKRGLNLAANAAVTAAAKGQGVLSEKLRSFSMQDL)
Cross-reacts with REEP1
Receptor expression-enhancing protein 1 (Spastic paraplegia 31 protein) Receptor expression-enhancing protein 2
Reep1 D6Ertd253e C2orf23 SPG31 Reep2 C5orf19 SGC32445
TC Supernatant: AB_2315910
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.