Human Mouse Rat
ICC IHC WB
QKI5 is a member of the Signal Transduction and Activation of RNA proteins (STAR proteins) family. QKI5, QKI6 QKI7 and QKI7b are alternatively spliced mRNAs from the QKI1 gene. QKI5 is a RNA-binding protein. QKI5 has roles in the regulation of splicing, export and stability of mRNA. It is involved in myelinization. It is a nuclear isoform and contains a C-terminal nuclear localization signal. Diseases associated with this gene include Angiocentric Glioma, 6Q Terminal Deletion Syndrome .and Schizophrenia.
Synthetic peptide amino acids 315-331 (ATKVRRHDMRVHPYQRI, with nuclear localization signal underlined) of human QKI-5 (also known as Protein quaking, HqkI and Hqk, accession number Q96PU); Mouse: 100% identity (17/17 amino acids identical); Rat: 100% identity (17/17 amino acids identical) No identity with QKI-6, QKI-7 and QKI-7b
Does not cross-react with QKI-6, QKI-7 or QKI-7bCross-reacts with other STAR proteins containing similar nuclear localization signals
Qki Qk QKI HKQ Qk1 Qka1
TC Supernatant: AB_10676099
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
40 kDa (and others)
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.