Products: Primary Antibodies

Anti-QKI-5 Antibody (N195A/16)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-232
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-232
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC IHC WB

Target Description:

QKI5 is a member of the Signal Transduction and Activation of RNA proteins (STAR proteins) family. QKI5, QKI6 QKI7 and QKI7b are alternatively spliced mRNAs from the QKI1 gene. QKI5 is a RNA-binding protein. QKI5 has roles in the regulation of splicing, export and stability of mRNA. It is involved in myelinization. It is a nuclear isoform and contains a C-terminal nuclear localization signal. Diseases associated with this gene include Angiocentric Glioma, 6Q Terminal Deletion Syndrome .and Schizophrenia.

Immunogen:

Synthetic peptide amino acids 315-331 (ATKVRRHDMRVHPYQRI, with nuclear localization signal underlined) of human QKI-5 (also known as Protein quaking, HqkI and Hqk, accession number Q96PU); Mouse: 100% identity (17/17 amino acids identical); Rat: 100% identity (17/17 amino acids identical) No identity with QKI-6, QKI-7 and QKI-7b

Cross Reactivity:

Does not cross-react with QKI-6, QKI-7 or QKI-7bCross-reacts with other STAR proteins containing similar nuclear localization signals

Protein Name(s):

QKI-5

Gene Name(s):

Qki Qk QKI HKQ Qk1 Qka1

Antibody Registry ID:

Purified: AB_10674117
TC Supernatant: AB_10676099


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Molecular Weight:

40 kDa (and others)


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.