Peroxisomal Biogenesis Factor 7 is encoded by the gene PEX7. PEX7 is a member of the WD repeat peroxin-7 family. PEX7 binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import. PEX7 is ubiquitously expressed with the highest levels in the pancreas, skeletal muscle, and heart. Diseases associated with PEX7 include Rhizomelic Chondrodysplasia Punctata, Type 1 and Peroxisome Biogenesis Disorder 9B.
Fusion protein amino acids 64-150 (WD1 and WD2 repeat domains) of human PEX7(also known as Peroxisomal targeting signal 2 receptor, PTS2 receptor, PTS2R, Peroxisomal biogenesis factor 7 and Peroxin-7, accession number O00628); Mouse: 94% identity (82/87 amino acids identical); Rat: 93% identity (81/87 amino acids identical) Less than 50% identity with other WD repeat-containing proteins
No cross-reactivity reported
TC Supernatant: AB_10674116
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.