Human Mouse Rat
ICC IHC WB
Fusion protein amino acids 1-322 (N-terminus) of human ZNF746 (also known as Zinc finger protein 746 and Zfp746, accession number Q6NUN9)
Mouse: 96% identity (312/323 amino acids identical)
>50% identity with ZNF783, ZNF282 and ZNF398
Does not cross-react with ZNF783 or ZNF398
Zinc finger protein 746 (Parkin-interacting substrate) (PARIS)
TC Supernatant: AB_10675299
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
Citations and References
- Liu Z, Liu Y, Gao R, Li H, Dunn T, Wu P, Smith RG, Sarkar PS, Fang X.. (2014), 'Ethanol suppresses PGC-1α expression by interfering with the cAMP-CREB pathway in neuronal cells. .' PLoS One. 10.1371/journal.pone.0104247. " "
- Silva DF, Selfridge JE, Lu J, E L, Roy N, Hutfles L, Burns JM, Michaelis EK, Yan S, Cardoso SM, Swerdlow RH.. (2013), 'Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines. .' Human Molecular Genetics. 10.1093/hmg/ddt247. " "
- Kang HC, Lee YI, Shin JH, Andrabi SA, Chi Z, Gagné JP, Lee Y, Ko HS, Lee BD, Poirier GG, Dawson VL, Dawson TM.. (2011), 'Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage. .' Proceedings of the National Academy of Science of the United States of America. 10.1073/pnas.1108799108. "