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Products: Primary Antibodies

Anti-Pannexin-2 Antibody (N121A/31)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-213
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-213
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

IHC WB

Target Description:

Pannexin 2 is encoded by the gene PANX2. PANX2 is a member of the pannexin family. PANX2 combines with pannexin 1 to form cell type-specific gap junctions with distinct properties. PANX2 is expressed in the eye, thyroid, prostate, kidney, liver, and central nervous system. Diseases associated with PANX2 include Oculodentodigital Dysplasia and Chronic Closed-Angle Glaucoma.

Immunogen:

Fusion protein amino acids 11-664 (all but first 10 amino acids, encompassing extracellular and cytoplasmic domains) of rat Pannexin-2 (also known as Panx2 and Px2, accession number P60571); Mouse: 98% identity (645/657 amino acids identical); Human: 91% identity (564/615 amino acids identical); Less than 30% identity with Pannexin-1 and Pannexin-3

Cross Reactivity:

Does not cross-react with Pannexin-1 or Pannexin-3

Protein Name(s):

Pannexin-2

Gene Name(s):

Panx2 Px2

Antibody Registry ID:

Purified: AB_2283425
TC Supernatant: AB_10673509


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

70 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.