Products: Primary Antibodies
PRODUCT OPTIONS
Catalog # | Option | Volume | Concentration | Price* | |
---|---|---|---|---|---|
Catalog # 75-042 |
Option Purified |
Volume 100 µL |
Concentration 1 mg/mL |
Price $269.00 |
|
Catalog # 73-042 |
Option TC Supernatant |
Volume 5 mL |
Concentration Lot dependent |
Price $269.00 |
Overview
NeuroMab
Monoclonal
Mouse
IgG1
Human Mouse Rat
ICC IHC WB
Synthetic peptide of amino acids 131-150 of human Pancortin (GLESKFKQVEE SHKQHLARQ, also known as Noelin, Neuronal olfactomedin-related ER localized protein, Noe1, Noel, Noel1, Olfactomedin-1, Olfm1, 1B426B and D2Sut1e, accession number Q99784)
Mouse: 95% identity (19/20 amino acids)
Rat: 95% identity (19/20 amino acids)
100% identity with isoforms Pancortin-2,Pancortin-3 and Pancortin-4
50% identity with Noelin-2 or Noelin-3
Noelin (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1)
OLFM1 NOE1 NOEL1
Purified: AB_2267633
TC Supernatant: AB_10674112
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
55-70 kDa (Pancortin-1 and -3),15-20 kDa (Pancortin-2 and -4)
Quality Control
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
Citations and References
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- Rice HC, Townsend M, Bai J, Suth S, Cavanaugh W, Selkoe DJ, Young-Pearse TL.. (2012), 'Pancortins interact with amyloid precursor protein and modulate cortical cell migration. .' Development. 10.1242/dev.082909. " "
- Bohr DC, Koch M, Kritzenberger M, Fuchshofer R, Tamm ER.. (2011), 'Increased expression of olfactomedin-1 and myocilin in podocytes during puromycin aminonucleoside nephrosis. .' Nephrol Dial Transplant.. 10.1093/ndt/gfq366. " "
- Cheng A, Arumugam TV, Liu D, Khatri RG, Mustafa K, Kwak S, Ling HP, Gonzales C, Xin O, Jo DG, Guo Z, Mark RJ, Mattson MP.. (2007), 'Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death. .' Journal of Neuroscience. 10.1523/JNEUROSCI.5154-06.2007. ".' Development. 10.1242/dev.082909." "
- Bohr DC, Koch M, Kritzenberger M, Fuchshofer R, Tamm ER.. (2011), 'Increased expression of olfactomedin-1 and myocilin in podocytes during puromycin aminonucleoside nephrosis. .' Nephrol Dial Transplant.. 10.1093/ndt/gfq366. " "
- Cheng A, Arumugam TV, Liu D, Khatri RG, Mustafa K, Kwak S, Ling HP, Gonzales C, Xin O, Jo DG, Guo Z, Mark RJ, Mattson MP.. (2007), 'Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death. .' Journal of Neuroscience. 10.1523/JNEUROSCI.5154-06.2007. "