Fusion protein amino acids 1-67 (N-terminus) of mouse Olig1(also known as Oligodendrocyte-specific bHLH transcription factor 1 and Oligo1, accession number Q9JKN5)
Rat: 97% identity (66/68 amino acids identical)
Human: 75% identity (54/72 amino acids identical)
<40% identity with Olig2
No cross-reactivity against Olig2
Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte-specific bHLH transcription factor 1)
TC Supernatant: AB_10674111
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.
Citations and References
- Ehmsen JT, Ma TM, Sason H, Rosenberg D, Ogo T, Furuya S, Snyder SH, Wolosker H.. (2013), 'D-serine in glia and neurons derives from 3-phosphoglycerate dehydrogenase. .' Journal of Neuroscience. 10.1523/JNEUROSCI.4914-12.2013. " "
- Xue Y, Ouyang K, Huang J, Zhou Y, Ouyang H, Li H, Wang G, Wu Q, Wei C, Bi Y, Jiang L, Cai Z, Sun H, Zhang K, Zhang Y, Chen J, Fu XD.. (), 'Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. .' Cell. 10.1016/j.cell.2012.11.045. " "
- Lujan E, Chanda S, Ahlenius H, Südhof TC, Wernig M.. (2012), 'Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. .' Proceedings of the National Academy of Science of the United States of America. 10.1073/pnas.1121003109. " "
- Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Südhof TC, Wernig M.. (2010), 'Direct conversion of fibroblasts to functional neurons by defined factors. .' Nature. 10.1038/nature08797. "