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Products: Primary Antibodies

Anti-nNOS/NOS1 Antibody (L121/42)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-481
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-481
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2b

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

IHC WB

Target Description:

Nitric Oxide Synthase 1 is encoded by the gene NOS1. NOS1 is a member of the NOS family. NOS1 synthesizes nitric oxide from L-arginine, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. NOS1 is expressed ubiquitously, with high levels of expression in skeletal muscle. Diseases associated with NOS1 include Achalasia, Familial Esophageal and Pyloric Stenosis, Infantile Hypertrophic, 1.

Immunogen:

Fusion protein amino acids 350-720 of human NOS1

Protein Name(s):

NOS1 (Brain nitric oxide synthase) (Constitutive NOS) (Neuronal NOS) (Peptidyl-cysteine S-nitrosylase NOS1)

Gene Name(s):

NOS1

Antibody Registry ID:

Purified: AB_2744559
TC Supernatant: AB_2651160


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

155-165 kDa for full-length protein, smaller fragments possible due to proteolysis and/or variable sample preparation


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.