Human Mouse Rat
Synthetic peptide amino acids 208-223 (YYLR[pT]FGHN[pT]MDAVPR) of human NKCC1 (also known as Na-K-Cl symporter, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1, Solute carrier family 12 member 2 and Slc12a2, accession number P55011)
Mouse: 100% identity (16/16 amino acids identical)
Rat: 100% identity (16/16 amino acids identical)
>90% identity with NKCC2
>70% identity with NKCC3
Cross-reacts with non-phosphorylated protein by ELISA
Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1)
TC Supernatant: AB_10675296
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
Citations and References
- Campbell SL, Robel S, Cuddapah VA, Robert S, Buckingham SC, Kahle KT, Sontheimer H.. (2015), 'GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy. .' Glia. 10.1002/glia.22730. " "
- Antoine MW, Hübner CA, Arezzo JC, Hébert JM.. (2013), 'A causative link between inner ear defects and long-term striatal dysfunction. .' Science. 10.1126/science.1240405. "