Products: Primary Antibodies

Anti-NGL-3/LRRC4B Antibody (N51/6)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-085
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-085
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC IP WB

Target Description:

Leucine Rich Repeat Containing 4B is encoded by the gene LRRC4B. LRRC4B is a synaptic adhesion protein that regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner. LRRC4B is expressed in the brain. No disorders were found to be associated with LRRC4B.

Immunogen:

Fusion protein amino acids 598-709 of rat NGL-3 (Leucine-rich repeat-containing 4B protein (Lrrc4B), accession number XP_218615); Mouse: 100% identity (112/112 amino acids identical); Human: 94% identity (105/112 amino acids identical)

Cross Reactivity:

No cross-reactivity against NGL-1 or NGL-2

Protein Name(s):

NGL-3/LRRC4B

Gene Name(s):

Lrrc4b Lrig4

Antibody Registry ID:

Purified: AB_2137617
TC Supernatant: AB_10697883


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

100 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.