Human Mouse Rat
Synthetic peptide amino acids 47-64 (ASSLGAHHIHHFHGSSKH, extracellular N-terminus) of rat Neurexin-1-Beta (accession number Q63373)
Human: 100% identity (18/18 amino acids identical)
>60% identity with Neurexin-2-Beta
Does not cross-react with Neurexin-2-Beta
Neurexin-1-beta (Neurexin I-beta)
TC Supernatant: AB_10672978
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.
Citations and References
- Yamagata M, Duan X, Sanes JR.. (2018), 'Cadherins Interact With Synaptic Organizers to Promote Synaptic Differentiation. .' Frontiers in Molecular Neuroscience. 10.3389/fnmol.2018.00142. " "
- Futai K, Doty CD, Baek B, Ryu J, Sheng M.. (2013), 'Specific trans-synaptic interaction with inhibitory interneuronal neurexin underlies differential ability of neuroligins to induce functional inhibitory synapses. .' Journal of Neuroscience. 10.1523/JNEUROSCI.1811-12.2013. " "
- Yamagata M, Sanes JR.. (2012), 'Transgenic strategy for identifying synaptic connections in mice by fluorescence complementation (GRASP). .' Frontiers in Molecular Neuroscience. 10.3389/fnmol.2012.00018. "