Neuregulin 1 is encoded by the gene NRG1. NRG1 is a member of the neuregulin family. NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. NRG1 is expressed in the nervous system, intestine, muscle, and heart. Diseases associated with NRG1 include Schizphrenia 6 and Lung Cancer.
Fusion protein amino acids 14-117 (extracellular N-terminus) of human Neuregulin-1(also known as NRG1, Neu differentiation factor, NDF, Heregulin, HRG, HGL, Breast cancer cell differentiation factor p45, Acetylcholine receptor-inducing activity, ARIA, Glial growth factor, GGF, Sensory and motor-neuron-derived factor or SMDF, accession number Q02297); Rat: 91% identity (95/104 amino acids identical); Mouse: 90%identity (91/104 amino acids identical); Less than 40% identity with NRG2
No cross-reactivity reported
Neuregulin-HBD (Heparin binding domain, Type I/II)
NRG1 GGF HGL HRGA NDF SMDF
TC Supernatant: AB_2154679
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.