Products: Primary Antibodies

Anti-Kv6.1 Antibody (N474/27)

from NeuroMab

PRODUCT OPTIONS

Brand	Catalog #	Option	Volume	Concentration	Price
Brand	Catalog # 75-490	Option Purified	Volume 100 µL	Concentration 1 mg/mL	Price $275.00
Brand	Catalog # 73-490	Option TC Supernatant	Volume 5 mL	Concentration Lot dependent	Price $275.00

"TC Supernatant" vs. "Purified"

TC Supernatant
Hybridoma tissue-culture supernatant (5mL) generally containing 10-50 ug/mL monoclonal antibody (clone-dependent) can be a very economical choice. Supernatant is suitable for most applications including Western Blot, immunocytochemistry, immunohistochemistry etc. For applications requiring higher antibody concentration or purity (such as immunoprecipitation, microinjection, or conjugation) it is recommended that you purchase the purified form of the antibody (supplied at 1mg/mL).

Purified mAbs
Produced by in vitro bioreactor culture of hybridoma lines followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody at 1mg/mL.

Validation Images

Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Mouse

Applications:

ICC

Target Description:

Potassium voltage-gated channel modifier subfamily G member 1 is encoded by the gene KCNG1. KCNG1 is a member of the potassium channel family, G (TC 1.A.1.2) subfamily, Kv6.1/KCNG1 sub-subfamily. KCNG1 is a potassium channel subunit that does not form functional channels by itself. It can form functional heterotetrameric channels with KCNB1. KCNG1 modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1. KCNG1 is expressed in skeletal muscle. Diseases associated with KCNG1 include Colon Small Cell Carcinoma and Fragile X Syndrome.

Immunogen:

Fusion protein amino acids 1-227 (cytoplasmic N-terminus) of mouse Kv6.1 (also known as Potassium voltage-gated channel subfamily G member 1, Voltage-gated potassium channel subunit Kv6.1, kH2 and Kcng1, accession number A2BDX4) Rat: 97% identity (220/227 amino acids identical)
Human: 89% identity (202/227 amino acids identical)
<50% identity with Kv6.4/KCNG4 and other Kv channels

Protein Name(s):

Kv6.1 (Potassium voltage-gated channel subfamily G member 1) (Voltage-gated potassium channel subunit Kv6.1)

Gene Name(s):

Kcng1

Antibody Registry ID:

Purified: AB_2744563
TC Supernatant: AB_2716258

Antibody Validation and Application Notes

This antibody has been validated using the following assays:

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Quality Control

The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.