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Products: Primary Antibodies

Anti-Kv1.4 K+ channel Antibody (K13/31)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-010
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-010
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

IHC IP WB

Target Description:

Potassium voltage-gated channel subfamily A member 4 or Kv1.4 is encoded by the gene KCNA4. Kv1.4 is a potassium channel subunit is a member of the potassium channel, voltage-gated, shaker-related subfamily. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.4 is expressed in brain, and at lower levels in the testis, lung, kidney, colon, heart and adrenal tissue. In brain, Kv1.4 is located in the soma, dendrite and axon terminus of neurones in most regions of the brain.

Immunogen:

Synthetic peptide 13-37 of rat Kv1.4 (NSHMPYGYAAQARARERERLAHSR; accession number P15385); Human: 100% identity; Mouse: 100% identity

Cross Reactivity:

No cross-reactivity against Kv1.1, Kv1.2, Kv1.3, Kv1.5 and Kv1.6 expressed in transfected cells

Protein Name(s):

Kv1.4 K+ channel

Gene Name(s):

Kcna4

Antibody Registry ID:

Purified: AB_2249726
TC Supernatant: AB_10673576


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

98 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.