Human Mouse Rat
Potassium inwardly rectifying channel subfamily J member 9 is encoded by the gene KCNJ9. KCNJ9 is a member of the inward rectifier-type potassium channel (TC 1.A.2.1) family, KCNJ9 subfamily. KCNJ9 is an integral membrane protein and inward-rectifier type potassium channel, which has a greater tendency to allow potassium to flow into the cell rather than out of the cell. KCNJ9 is controlled by G-proteins and associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. KCNJ9 is expressed in the brain and skeletal muscle. Diseases associated with KCNJ9 include Pendred Syndrom and Seizures, Sensorineural Deafness, Ataxia, Mental Retardation, and Electrolyte Imbalance.
Fusion protein amino acids 1-21 and 341-393 (fusion of cytoplasmic N- and C-termini) of mouse Kir3.3 (also known as Inward rectifier K(+) channel Kir3.3, Potassium channel, inwardly rectifying subfamily J member 9, G protein-activated inward rectifier potassium channel 3, Kcnj9 and Girk3, accession number P48543)
Inward rectifier K(+) channel Kir3.3 (Potassium channel, inwardly rectifying subfamily J member 9) (G protein-activated inward rectifier potassium channel 3) (Kcnj9) (Girk3)
TC Supernatant: AB_2619638
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.