Human Mouse Rat
IHC IP WB
Kv Channel Interacting Protein 2, Kchip2 potassium channel subunit, or potassium channel auxiliary subunit KCHIP2b is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. Kchip2 is a calcium binding protein and an integral subunit component of native Kv4 channel complexes. Kchip2 is primarily expressed in heart tissue but is also found in brain. Diseases associated with KCNIP2 include Spinocerebellar Ataxia Type 19/22, Brugada Syndrome, long qt syndrome 1, and dilated cardiomyopathy.
Fusion protein amino acids 1-252 (full length) of rat KChIP2b (accession number AAF81756); Human: 96% identity (244/252 amino acids); Mouse=100% identity
No cross-reactivity against rat KChIPs 1,3
KChIP2b K+ channel
TC Supernatant: AB_10671304
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.