Products: Primary Antibodies

Anti-KChIP2b K+ channel Antibody (K60/73)

from NeuroMab

PRODUCT OPTIONS

Brand	Catalog #	Option	Volume	Concentration	Price
Brand	Catalog # 75-004	Option Purified	Volume 100 µL	Concentration 1 mg/mL	Price $275.00
Brand	Catalog # 73-004	Option TC Supernatant	Volume 5 mL	Concentration Lot dependent	Price $275.00

"TC Supernatant" vs. "Purified"

TC Supernatant
Hybridoma tissue-culture supernatant (5mL) generally containing 10-50 ug/mL monoclonal antibody (clone-dependent) can be a very economical choice. Supernatant is suitable for most applications including Western Blot, immunocytochemistry, immunohistochemistry etc. For applications requiring higher antibody concentration or purity (such as immunoprecipitation, microinjection, or conjugation) it is recommended that you purchase the purified form of the antibody (supplied at 1mg/mL).

Purified mAbs
Produced by in vitro bioreactor culture of hybridoma lines followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody at 1mg/mL.

Validation Images

Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:

IHC IP WB

Target Description:

Kv Channel Interacting Protein 2, Kchip2 potassium channel subunit, or potassium channel auxiliary subunit KCHIP2b is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. Kchip2 is a calcium binding protein and an integral subunit component of native Kv4 channel complexes. Kchip2 is primarily expressed in heart tissue but is also found in brain. Diseases associated with KCNIP2 include Spinocerebellar Ataxia Type 19/22, Brugada Syndrome, long qt syndrome 1, and dilated cardiomyopathy.

Immunogen:

Fusion protein amino acids 1-252 (full length) of rat KChIP2b (accession number AAF81756); Human: 96% identity (244/252 amino acids); Mouse=100% identity

Cross Reactivity:

No cross-reactivity against rat KChIPs 1,3

Protein Name(s):

KChIP2b K+ channel

Gene Name(s):

Kcnip2 Kchip2

Antibody Registry ID:

Purified: AB_2280942
TC Supernatant: AB_10671304

Antibody Validation and Application Notes

This antibody has been validated using the following assays:

Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:

This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

35 kDa

Quality Control

The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.