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Products: Primary Antibodies

Anti-KChIP2b K+ channel Antibody (K60/73)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-004
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-004
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

IHC IP WB

Target Description:

Kv Channel Interacting Protein 2, Kchip2 potassium channel subunit, or potassium channel auxiliary subunit KCHIP2b is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. Kchip2 is a calcium binding protein and an integral subunit component of native Kv4 channel complexes. Kchip2 is primarily expressed in heart tissue but is also found in brain. Diseases associated with KCNIP2 include Spinocerebellar Ataxia Type 19/22, Brugada Syndrome, long qt syndrome 1, and dilated cardiomyopathy.

Immunogen:

Fusion protein amino acids 1-252 (full length) of rat KChIP2b (accession number AAF81756); Human: 96% identity (244/252 amino acids); Mouse=100% identity

Cross Reactivity:

No cross-reactivity against rat KChIPs 1,3

Protein Name(s):

KChIP2b K+ channel

Gene Name(s):

Kcnip2 Kchip2

Antibody Registry ID:

Purified: AB_2280942
TC Supernatant: AB_10671304


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

35 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.