Products: Primary Antibodies

Anti-GABA-A-R-Gamma2L (N452/69)


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PRODUCT OPTIONS

Catalog # Option Concentration Price*
Catalog #
75-442
Option
Purified
Concentration
1 mg/mL
Price
$205.00
Catalog #
73-442
Option
TC Supernatant
Concentration
Lot dependent
Price
$180.00

Overview

Brand:

NeuroMab

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2a

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC IHC WB

Immunogen:

Fusion protein amino acids 360-445 (cytoplasmic C-terminus) of human GABA-A-R-Gamma2L (also known as Gamma-aminobutyric acid receptor subunit gamma-2 and GABRG2, accession number P18507-2)
Mouse: 100% identity (86/86 amino acids identical)
Rat: 100% identity (86/86 amino acids identical)90% identity with GABA-A-R-Gamma2S (amino acids 377-384, LLRMFSFK, unique to Gamma2L)
50% identity with GABA-A-R-Gamma1 and GABA-A-R-Gamma3

Cross Reactivity:

Does not cross-react with GABA-A-R-Gamma2S, GABA-A-R-Gamma1 or GABAA-A-R-Gamma3

Protein Name(s):

Gamma-aminobutyric acid receptor subunit gamma-2 (GABA(A) receptor subunit gamma-2)

Gene Name(s):

GABRG2

Antibody Registry ID:

Purified: AB_2617122
TC Supernatant: AB_2566822


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine/immunofluorescence staining pattern when used to stain brain sections.

Expected Banding Pattern:

45 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.