Products: Primary Antibodies

Anti-FGF13/FHF2 Antibody (N91/27)

from NeuroMab

PRODUCT OPTIONS

Brand	Catalog #	Option	Volume	Concentration	Price
Brand	Catalog # 75-134	Option Purified	Volume 100 µL	Concentration 1 mg/mL	Price $275.00
Brand	Catalog # 73-134	Option TC Supernatant	Volume 5 mL	Concentration Lot dependent	Price $275.00

"TC Supernatant" vs. "Purified"

TC Supernatant
Hybridoma tissue-culture supernatant (5mL) generally containing 10-50 ug/mL monoclonal antibody (clone-dependent) can be a very economical choice. Supernatant is suitable for most applications including Western Blot, immunocytochemistry, immunohistochemistry etc. For applications requiring higher antibody concentration or purity (such as immunoprecipitation, microinjection, or conjugation) it is recommended that you purchase the purified form of the antibody (supplied at 1mg/mL).

Purified mAbs
Produced by in vitro bioreactor culture of hybridoma lines followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody at 1mg/mL.

Validation Images

Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:

ICC IP WB

Target Description:

Fibroblast growth factor 13, FHF2 or FGF13 is encoded by the gene FGF13. FHF2 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF13 is expressed in the nervous system and other tissues. Diseases associated with FGF13 include X-Linked Congenital Generalized Hypertrichosis and Wildervanck Syndrome.

Immunogen:

Fusion protein amino acids 53-245 of human FGF13a (also known as fibroblast growth factor homologous factor 2a or FHF2a, accession number Q92913); Mouse: 99% identity (192/193 amino acids identical); Rat: 97% identity (183/188 amino acids identical); 97% identity with FGF13b (184/188 amino acids identical); Greater than 60% identity with FGF11, FGF12 and FGF14

Cross Reactivity:

Cross-reacts with FGF13a and FGF13bDoes not cross-react with FGF11, FGF12 or FGF14 expressed in heterologous cells

Protein Name(s):

FGF13/FHF2

Gene Name(s):

FGF13 FHF2

Antibody Registry ID:

Purified: AB_2104047
TC Supernatant: AB_10675138

Antibody Validation and Application Notes

This antibody has been validated using the following assays:

Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Molecular Weight:

28 kDa

Quality Control

The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.