Human Mouse Rat
Fibroblast growth factor 12, FHF1 or FGF12 is encoded by the gene FGF12. FHF1 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF12 has been found to be expressed in the brain, eye and testis. Diseases associated with FGF12 include Early Infantile Epileptic Encephalopathy, Ebstein anomaly and Autosomal Dominant Deafness.
Fusion protein amino acids 1-243 (full-length) of human FGF12a (also known as fibroblast growth factor homologous factor 12a or FHF1a, accession number P61328)
Rat: 100% identity (243/243 amino acids identical); Mouse: 100% identity (243/243 amino acids identical); 60% identity with FGF11/FHF3, FGF13/FHF2 and FGF14/FHF4High identity with FGF12b/FHF1b
Cross-reacts with FGF12b/FHF1bDoes not cross-react with FGF11/FHF3, FGF13/FHF2 or FGF14/FHF4
FGF12 FGF12B FHF1
TC Supernatant: AB_10675137
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.