Human Mouse Rat
ICC IP WB
Fibroblast growth factor 11, FHF3 or FGF11 is encoded by the gene FGF11. FHF3 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FHF3 is expressed in the Nervous system. Diseases associated with FGF11 include Congenital Myasthenic Syndrome 2A and Congenital Myasthenic Syndrome.
Fusion protein amino acids 55-216 of human FGF11a (also known as fibroblast growth factor homologous factor 3a or FHF3a number Q92914); Mouse: 96% identity (157/162 amino acids identical); Rat: 96% identity (156/162 amino acids identical); Greater than 60% identity with FGF12, FGF13 and FGF14
Does not cross-react with FGF12, FGF13 or FGF14 in heterologous cells
TC Supernatant: AB_10671702
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.