Fusion protein amino acids 1-387 (full-length) of human DNMT3L (also known as DNA (cytosine-5)-methyltransferase 3-like, accession number BAA95556)
Rat: 66% identity (250/377 amino acids identical)
Mouse: 65% identity (242/371 amino acids identical)
~40% identity with DNMT3A and DNMT3B
No cross-reactivity against DNMT3A or DNMT3B
DNA (cytosine-5)-methyltransferase 3-like
TC Supernatant: AB_10673155
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.
Citations and References
- Satterlee JS, Beckel-Mitchener A, McAllister K, Procaccini DC, Rutter JL, Tyson FL, Chadwick LH.. (2015), 'Community resources and technologies developed through the NIH Roadmap Epigenomics Program. .' Methods Mol Biol.. 10.1007/978-1-4939-1804-1_2. "