Human Mouse Rat
Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer (also known as Dicer1, DCR, DCR-1, Double-strand-specific ribonuclease, Helicase with RNase motif, HERNA, Helicase MOI and KIAA0928, accession number Q8R418)
Human: 99% identity (257/262 amino acids identical)
Rat: 99% identity (257/262 amino acids identical)
Endoribonuclease Dicer (EC 18.104.22.168) (Double-strand-specific ribonuclease mDCR-1)
Dicer1 Dicer Mdcr
TC Supernatant: AB_10673275
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
Citations and References
- Hsu PK, Xu B, Mukai J, Karayiorgou M, Gogos JA.. (2015), 'The BDNF Val66Met variant affects gene expression through miR-146b. .' Neurobiology of Disease. 10.1016/j.nbd.2015.03.004. " "
- Satterlee JS, Beckel-Mitchener A, McAllister K, Procaccini DC, Rutter JL, Tyson FL, Chadwick LH.. (2015), 'Community resources and technologies developed through the NIH Roadmap Epigenomics Program. .' Methods Mol Biol.. 10.1007/978-1-4939-1804-1_2. " "
- Huang YW, Ruiz CR, Eyler EC, Lin K, Meffert MK.. (2012), 'Dual regulation of miRNA biogenesis generates target specificity in neurotrophin-induced protein synthesis. .' Cell. 10.1016/j.cell.2012.01.036. "