Products: Primary Antibodies

Anti-Dicer (N167/7)

PRODUCT OPTIONS

Catalog #	Option	Concentration	Price*
Catalog # 75-196	Option Purified	Concentration 1 mg/mL	Price $205.00
Catalog # 73-196	Option TC Supernatant	Concentration Lot dependent	Price $180.00

* Prices shown reflect any applicable non-profit/academic discount. NeuroMab antibodies will have higher for-profit/distribution and orders placed online will need to be adjusted. Please inquire with us for more information.

"TC Supernatant" vs. "Purified"

TC Supernatant
Hybridoma tissue-culture supernatant (5mL) generally containing 20-60 ug/mL monoclonal antibody (mAb). Supernatant is suitable for most applications, including Western Blot, immunocytochemistry, immunohistochemistry, etc., and is a very economical choice compared to competitor offerings. For applications requiring higher antibody concentration or purity (such as immunoprecipitation, microinjection, or conjugation) it is recommended that you purchase the purified form of the antibody (supplied at 1mg/mL).

Purified mAbs
Produced by in vitro bioreactor culture of hybridoma lines followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody at 1mg/mL.

Overview

Brand:

NeuroMab

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:

ICC WB

Immunogen:

Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer (also known as Dicer1, DCR, DCR-1, Double-strand-specific ribonuclease, Helicase with RNase motif, HERNA, Helicase MOI and KIAA0928, accession number Q8R418)
Human: 99% identity (257/262 amino acids identical)
Rat: 99% identity (257/262 amino acids identical)

Cross Reactivity:

None Reported

Protein Name(s):

Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1)

Gene Name(s):

Dicer1 Dicer Mdcr

Antibody Registry ID:

Purified: AB_2093085
TC Supernatant: AB_10673275

Antibody Validation and Application Notes

This antibody has been validated using the following assays:

Knockout Validation:

This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).

Western Blot:

This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.

Expected Banding Pattern:

215 kDa

Quality Control

The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.