ICC IHC WB
This antibody recognizes both Cyclic Nucleotide Gated Channel Subunit Alpha 1 and Cyclic Nucleotide Gated Channel Subunit Alpha 3, which are both members of the cyclic nucleotide-gated cation channel family. These ion channels function in response to the binding of cyclic nucleotides. CNG channels are nonselective cation channels that are found in the membranes of various tissue and cell types, and are significant in sensory transduction as well as cellular development.
Fusion protein amino acids 535-637 (cytoplasmic C-terminus) of goldfish CNG (also known as cGMP-gated cation channel alpha subunit, accession number AAO16601); Zebrafish CNGA3: 46% identity (47/103 amino acids identical); Rat CNGA3: 46% identity (47/103 amino acids identical); Mouse CNGA3: 46% identity (47/103 amino acids identical)
No cross-reactivity reported
CNGA1 and CNGA3
TC Supernatant: AB_10672374
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
80 kDa(size will vary depending on species and isoform)
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.