ICC IHC WB
Fusion protein amino acids 535-637 (cytoplasmic C-terminus) of goldfish CNG (also known as cGMP-gated cation channel alpha subunit, accession number AAO16601)
Zebrafish CNGA3: 46% identity (47/103 amino acids identical)
Rat CNGA3: 46% identity (47/103 amino acids identical)
Mouse CNGA3: 46% identity (47/103 amino acids identical)
Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3)
TC Supernatant: AB_10672374
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
80 kDa(size will vary depending on species and isoform)
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.
Citations and References
- Hanke-Gogokhia C, Wu Z, Gerstner CD, Frederick JM, Zhang H, Baehr W.. (2016), 'Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors. .' The Journal of Biological Chemistry. 10.1074/jbc.M115.710954. " "
- Ying G, Avasthi P, Irwin M, Gerstner CD, Frederick JM, Lucero MT, Baehr W.. (2014), 'Centrin 2 is required for mouse olfactory ciliary trafficking and development of ependymal cilia planar polarity. .' Journal of Neuroscience. 10.1523/JNEUROSCI.0067-14.2014. " "
- Christiansen JR, Kolandaivelu S, Bergo MO, Ramamurthy V.. (2011), 'RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments. .' Proceedings of the National Academy of Science of the United States of America. 10.1073/pnas.1103627108. " "
- Khan S, Perry C, Tetreault ML, Henry D, Trimmer JS, Zimmerman AL, Matthews G.. (2010), 'A novel cyclic nucleotide-gated ion channel enriched in synaptic terminals of isotocin neurons in zebrafish brain and pituitary. .' Neuroscience. 10.1016/j.neuroscience.2009.09.040. "