Human Mouse Rat
IHC IP WB
Calcium-activated potassium channel subunit beta-4, Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 4 or BKBeta4 is encoded by the gene KCNMB4. BKbeta4 can bind to KCNMA1 to form a channel in the calcium activated large conductance (MaxiK channel) family. BKbeta4 acts to modulate the calcium sensitivity and gating kinetics of KCNMA1. It is expressed in brain and CNS.
Fusion protein amino acids 45-167 (entire extracellular domain) of mouse BKBeta4 (accession number Q9JIN6); Rat: 100% identity (123/123 amino acids identical); Human: 95% identity (117/123 amino acids identical)
No cross-reactivity against BKBeta1, BKBeta2 or BKBeta3
BKbeta4 K+ channel
TC Supernatant: AB_10675133
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.