Anti-ATAT1 Antibody (N347/42)

Name: Anti-ATAT1 Antibody
Brand: NeuroMab
SKU: 75-426
Price: 337.0 USD
Availability: InStock

Our mouse ATAT1 monoclonal antibody from NeuroMab is produced in-house from clone N347/42. It detects human, mouse, and rat ATAT1 and is purified by Protein A chromatography. KO validated. Works in WB, ICC, ELISA.

Immunoblot against crude membranes from adult rat brain (RBM), mouse brain (MBM) and wild-type (WT) and ATAT1 knockout (KO) mouse brains probed with N347/42 (left) or N52A/42 (right) TC supe. WT and KO mouse brains courtesy of Andrea Aguilar and Max Nachury (Stanford

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-426

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

ATAT1

Scientific Background

Alpha-tubulin N-acetyltransferase 1 or ATAT is encoded by the gene ATAT1 and is an enzyme which belongs to the acyltransferase family. ATAT1 functions to acetylate alpha tubulin at Lysine 40. ATAT1 is thought to be involved in microtubule growth, for instance during chemotaxis and the formation of cilium. ATAT1 exists in multiple isotypes. ATAT1 is expressed in many tissues including brain, kidney, retina and testis. Diseases associated with ATAT1 include Von Willebrand Disease, Type 3 and Blood Coagulation Disease.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N347/42

Isotype

IgG1

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

ATAT1 C6orf134 MEC17 Nbla00487

Molecular Weight

40-45 kDa

Immunogen

Fusion protein amino acids 2-236 (N-acetyltransferase domain) of human ATAT1 (accession number Q5SQI0) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2637013

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Alpha-tubulin N-acetyltransferase 1 (Alpha-TAT) (Alpha-TAT1) (TAT) (EC 2.3.1.108) (Acetyltransferase mec-17 homolog)

UniProt ID

Q5SQI0

Shipping

Shipped on ice packs

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Anti-ATAT1 Antibody (N347/42)

SKU: 75-426

Product Details

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