When placing orders, please note whether your facility is currently receiving packages

Products: Primary Antibodies

Anti-ATAT1 Antibody (N347/42)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-426
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-426
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC WB

Target Description:

Alpha-tubulin N-acetyltransferase 1 or ATAT is encoded by the gene ATAT1 and is an enzyme which belongs to the acyltransferase family. ATAT1 functions to acetylate alpha tubulin at Lysine 40. ATAT1 is thought to be involved in microtubule growth, for instance during chemotaxis and the formation of cilium. ATAT1 exists in multiple isotypes. ATAT1 is expressed in many tissues including brain, kidney, retina and testis. Diseases associated with ATAT1 include Von Willebrand Disease, Type 3 and Blood Coagulation Disease.

Immunogen:

Fusion protein amino acids 2-236 (N-acetyltransferase domain) of human ATAT1 (also known as Alpha-tubulin N-acetyltransferase 1, Acetyltransferase mec-17 homolog, Alpha-TAT, Alpha-TAT1, TAT, MEC17, C6orf134 and Nbla00487, accession number Q5SQI0)
Rat: 94% identity (222/235 amino acids identical)
Mouse: 94% identity (221/235 amino acids identical)

Protein Name(s):

Alpha-tubulin N-acetyltransferase 1 (Alpha-TAT) (Alpha-TAT1) (TAT) (EC 2.3.1.108) (Acetyltransferase mec-17 homolog)

Gene Name(s):

ATAT1 C6orf134 MEC17 Nbla00487

Antibody Registry ID:

Purified: AB_2637013
TC Supernatant: AB_2531888


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Knockout Validation:

This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).

Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

40-45 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.