Human Mouse Rat
Alpha-tubulin N-acetyltransferase 1 or ATAT is encoded by the gene ATAT1 and is an enzyme which belongs to the acyltransferase family. ATAT1 functions to acetylate alpha tubulin at Lysine 40. ATAT1 is thought to be involved in microtubule growth, for instance during chemotaxis and the formation of cilium. ATAT1 exists in multiple isotypes. ATAT1 is expressed in many tissues including brain, kidney, retina and testis. Diseases associated with ATAT1 include Von Willebrand Disease, Type 3 and Blood Coagulation Disease.
Fusion protein amino acids 2-236 (N-acetyltransferase domain) of human ATAT1 (also known as Alpha-tubulin N-acetyltransferase 1, Acetyltransferase mec-17 homolog, Alpha-TAT, Alpha-TAT1, TAT, MEC17, C6orf134 and Nbla00487, accession number Q5SQI0)
Rat: 94% identity (222/235 amino acids identical)
Mouse: 94% identity (221/235 amino acids identical)
Alpha-tubulin N-acetyltransferase 1 (Alpha-TAT) (Alpha-TAT1) (TAT) (EC 126.96.36.199) (Acetyltransferase mec-17 homolog)
ATAT1 C6orf134 MEC17 Nbla00487
TC Supernatant: AB_2531888
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.