Immunoblot against extracts of COS cells transiently transfected with GFP-tagged zebrafish VSP (DrVSP) or untagged Xenopus (XtVSP, XlVSP and XlVSP2), sea squirt (CiVSP), chicken VSP (GgVSP) or Kv2.1 plasmid probed with N432/63 (left) or N52A/42 (right) TC supe..
Bulk Order Anti-VSP/TPTE Antibody
TPTEs (transmembrane phosphatases with tensin homology) aka VSPs (voltage sensing phosphatases) catalyze the dephosphorylation of phosphatidylinositol phosphates (PIPs) that regulate diverse aspects of cell membrane physiology including cell division, growth and migration (Ratzan W. et al., 2019). TPTEs are also thought to be involved in signal transduction pathways of the endocrine or spermatogenetic function of the testis (Chen H. et al., 1999).
Purified by Protein A chromatography
Fusion protein amino acids 153-335 of zebrafish TPTE (accession number Q4V9E4) produced recombinantly in E. Coli
Chicken, Xenopus, Zebrafish
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
No cross-reactivity reported
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from date of receipt
Shipped on ice packs
Transmembranephosphatase with tensin homology (voltage-sensing phosphoinositide phosphatase) ( VSP)