Anti-VSP/TPTE Antibody (N432/63)

Name: Anti-VSP/TPTE Antibody
Brand: NeuroMab
SKU: 75-486
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Chicken, Xenopus, Zebrafish

Clone

N432/63

Applications

ICC, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

TPTE

Molecular Weight

40-60 kDa

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Immunoblot against extracts of COS cells transiently transfected with GFP-tagged zebrafish VSP (DrVSP) or untagged Xenopus (XtVSP, XlVSP and XlVSP2), sea squirt (CiVSP), chicken VSP (GgVSP) or Kv2.1 plasmid probed with N432/63 (left) or N52A/42 (right) TC supe..

Volume: 100 µL

Variant

Price:

$308

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Product Details

Target

VSP/TPTE

Target Description

TPTEs (transmembrane phosphatases with tensin homology) aka VSPs (voltage sensing phosphatases) catalyze the dephosphorylation of phosphatidylinositol phosphates (PIPs) that regulate diverse aspects of cell membrane physiology including cell division, growth and migration (Ratzan W. et al., 2019). TPTEs are also thought to be involved in signal transduction pathways of the endocrine or spermatogenetic function of the testis (Chen H. et al., 1999).

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N432/63

Isotype

IgG1

Applications

ICC, WB

Host Species

Mouse

Gene Name

TPTE

Molecular Weight

40-60 kDa

Antigen

Fusion protein amino acids 153-335 of zebrafish TPTE (accession number Q4V9E4) produced recombinantly in E. Coli

Species Reactivity

Chicken, Xenopus, Zebrafish

Antibody Registry ID

AB_2744561

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Transmembranephosphatase with tensin homology (voltage-sensing phosphoinositide phosphatase) ( VSP)

UniProt Details

UniProt (Human): P56180
UniProt (Immunogen Species): Q4V9E4

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Anti-VSP/TPTE Antibody (N432/63)

Available Conjugates

Anti-VSP/TPTE Antibody
SKU: 75-486

Bulk Order Anti-VSP/TPTE Antibody

Product Details

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Anti-VSP/TPTE Antibody (N432/63)

Available Conjugates

Anti-VSP/TPTE Antibody SKU: 75-486

Bulk Order Anti-VSP/TPTE Antibody

Product Details

Anti-VSP/TPTE Antibody
SKU: 75-486