Anti-VSP/TPTE Antibody (N432/21)

Name: Anti-VSP/TPTE Antibody
Brand: NeuroMab
SKU: 75-485
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

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Clonality

Monoclonal

Applications

Host Species

Mouse

Gene Name

TPTE

Molecular Weight

40-60 kDa

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Immunoblot against extracts of COS cells transiently transfected with GFP-tagged zebrafish VSP (DrVSP) or untagged Xenopus (XtVSP, XlVSP and XlVSP2), sea squirt (CiVSP), chicken VSP (GgVSP) or Kv2.1 plasmid probed with N432/21 (left) or N52A/42 (right) TC supe..

Product Details

Target

Transmembrane phosphatase with tensin homology (voltage-sensing phosphoinositide phosphatase) ( VSP)

Target Description

TPTEs (transmembrane phosphatases with tensin homology) aka VSPs (voltage sensing phosphatases) catalyze the dephosphorylation of phosphatidylinositol phosphates (PIPs) that regulate diverse aspects of cell membrane physiology including cell division, growth and migration (Ratzan W. et al., 2019). TPTEs are also thought to be involved in signal transduction pathways of the endocrine or spermatogenetic function of the testis (Chen H. et al., 1999).

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N432/21

Isotype

IgG2a

Applications

Host Species

Mouse

Gene Name

TPTE

Molecular Weight

40-60 kDa

Antigen

Fusion protein amino acids 153-335 of zebrafish TPTE (also known as Transmembrane phosphatase with tensin homology, voltage-sensing phosphoinositide phosphatase and VSP, accession number Q4V9E4)

Species Reactivity

Chicken, Xenopus, Zebrafish

Antibody Registry ID

AB_2744560

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Transmembranephosphatase with tensin homology (voltage-sensing phosphoinositide phosphatase) ( VSP)

UniProt Details

UniProt (Human): P18507
UniProt (Immunogen Species): P18507-2

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Anti-VSP/TPTE Antibody (N432/21)

Anti-VSP/TPTE Antibody
SKU: 75-485

Product Details

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Anti-VSP/TPTE Antibody (N432/21)

Anti-VSP/TPTE Antibody SKU: 75-485

Product Details

Anti-VSP/TPTE Antibody
SKU: 75-485