Vesicular glutamate transporter 3 (VGLUT3) or Solute Carrier Family 17 Member 8 is encoded by the gene SLC17A8 and belongs to the vesicular glutamate transporter family. Vglut3 transports glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. Vglut3 is expressed in many tissues including brain, kidney and liver. In brain, it is expressed within glutamatergic neurons in the amygdala, brainstem, cerebral cortex, dorsal root ganglia, dorsal spinal cord, hippocampus, and hypothalamus. Diseases associated with SLC17A8 include Deafness.
Purified by Protein A chromatography
Fusion protein amino acids 546-588 (cytoplasmic C-terminus) of rat VGlut3 (accession number NP_714947) produced recombinantly in E. Coli
Drosophila, Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL650 Ex: 655 nm, Em: 676 nm
No cross-reactivity reported
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8)