Vesicular glutamate transporter 3 (VGLUT3) or Solute Carrier Family 17 Member 8 is encoded by the gene SLC17A8 and belongs to the vesicular glutamate transporter family. Vglut3 transports glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. Vglut3 is expressed in many tissues including brain, kidney and liver. In brain, it is expressed within glutamatergic neurons in the amygdala, brainstem, cerebral cortex, dorsal root ganglia, dorsal spinal cord, hippocampus, and hypothalamus. Diseases associated with SLC17A8 include Deafness.
Fusion protein amino acids 546-588 (cytoplasmic C-terminus) of rat VGlut3 (accession number NP_714947); Mouse: 88% identity (38/43 amino acids identical); Human: 59% identity (26/44 amino acids identical)
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No cross-reactivity reported
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8)