Anti-VGlut2 Recombinant Chicken Chimeric mAb FL490 Conjugate (N29/29)

Name: Anti-VGlut2 Recombinant Chicken Chimeric mAb FL490 Conjugate
Brand: Aves Labs
SKU: 78-067-FL490
Price: 549.0 USD
Availability: InStock

Our chicken Anti-VGlut2 recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone N29/29. It detects electric ray, human, mouse and rat VGlut2, and is purified by affinity chromatography. It is great for use in IHC, ICC.

Anti-VGlut2 Recombinant Chicken Chimeric mAb FL490 Conjugate

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Applications

ICC, IHC

Host Species

Chicken

Conjugates and Formulations

Unconjugated

550

594

650

Carrier-Free

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Data Sheet

SKU: 78-067-FL490

Volume: 200 µL

Variant

Price:

$549.00

Quantity:

Ships: 1-5 business days

Product Details

Target

VGlut2

Scientific Background

Vesicular glutamate transporter 2 (Vglut2) is encoded by the gene Slc17a6 and belongs to the vesicular glutamate transporter family. Vglut2 is expressed in the thalamus, midbrain, brainstem, and spinal cord at synaptic vesicles. It functions to uptake glutamate into synaptic vesicles in excitatory neural cells. Altered expression of Vglut2 has been implicate in include Gnathodiaphyseal Dysplasia and tendinosis.

Format

Purified by affinity chromatography

Concentration

0.5 mg/mL

Clonality

Recombinant

Clone

N29/29

Isotype

IgY

Applications

ICC, IHC

Host Species

Chicken

Gene Name

Slc17a6 Dnpi Vglut2

Molecular Weight

60 kDa

Excitation / Emission

FL490 Ex: 491 nm, Em: 515 nm

Immunogen

Fusion protein amino acids 501-582 (cytoplasmic C-terminus) of rat VGlut2 (accession number Q9JI12) produced recombinantly in E. Coli

Immunogen Species

Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone N29/29 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone N29/29 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media and conjugated.

Buffer

1X PBS, 0.05% Sodium Azide pH 7.4

Dilution Ranges

IHC: 1:100-1:1000
ICC: 1:100-1:1000

Conjugate

490

Specificity

Does not cross-react with VGlut1 or VGlut3

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Vesicular glutamate transporter 2 (VGluT2) (Differentiation-associated BNPI) (Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter) (Solute carrier family 17 member 6)

UniProt ID

Q9JI12

Shipping

Shipped on ice packs

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Anti-VGlut2 Recombinant Chicken Chimeric mAb FL490 Conjugate (N29/29)

SKU: 78-067-FL490

Product Details

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