Anti-VGlut2 Antibody (N29/29)

Name: Anti-VGlut2 Antibody
Brand: NeuroMab
SKU: 75-067
Price: 285.0 USD
Availability: InStock

from NeuroMab Datasheet

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Clonality

Monoclonal

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Slc17a6 Dnpi Vglut2

Molecular Weight

60 kDa

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Transfected cell immunoblot: extracts of COS cells transiently transfected with untagged VGlut1, VGlut2, VGlut3 or Kv2.1 plasmid and probed with N29/29 (left) or N52A/42 (right) TC supe.

Immunoblot versus crude brain membranes from adult mouse (MBM), rat (RBM) and human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] and cerebellum [HBM(Cb)] probed with N29/29 (left) and N52A/42 (right) TC supe.

Immunofluorescence staining of adult rat cerebellum with N29/29 (green), N326D/2 (red) and Hoechst nuclear stain (blue).

Adult rat cerebellum and thalamus immunohistochemistry.

Transfected cell immunoblot: extracts of COS cells transiently transfected with untagged VGlut1, VGlut2, VGlut3 or Kv2.1 plasmid and probed with N29/29 (left) or N52A/42 (right) TC supe.

Product Details

Target

VGlut2

Target Description

Vesicular glutamate transporter 2 (Vglut2) is encoded by the gene Slc17a6 and belongs to the vesicular glutamate transporter family. Vglut2 is expressed in the thalamus, midbrain, brainstem, and spinal cord at synaptic vesicles. It functions to uptake glutamate into synaptic vesicles in excitatory neural cells. Altered expression of Vglut2 has been implicate in include Gnathodiaphyseal Dysplasia and tendinosis.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N29/29

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Slc17a6 Dnpi Vglut2

Molecular Weight

60 kDa

Antigen

Fusion protein amino acids 501-582 (cytoplasmic C-terminus) of rat VGlut2 (also known as Vesicular glutamate transporter 2, Differentiation-associated BNPI, Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, Dnpi, Solute carrier family 17 member 6 and Slc17a6, accession number Q9JI12); Mouse: 97% identity (80/82 amino acids identical); Human: 89% identity (73/82 amino acids identical) 50% identity with VGlut1 or VGlut3

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2239153

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Conjugate

Unconjugated

Specificity

Does not cross-react with VGlut1 or VGlut3

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Vesicular glutamate transporter 2 (VGluT2) (Differentiation-associated BNPI) (Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter) (Solute carrier family 17 member 6)

UniProt Details

UniProt (Human): Q9P2U8
UniProt (Immunogen Species): Q9JI12

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Anti-VGlut2 Antibody (N29/29)

Anti-VGlut2 Antibody
SKU: 75-067

Product Details

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Anti-VGlut2 Antibody (N29/29)

Anti-VGlut2 Antibody SKU: 75-067

Product Details

Anti-VGlut2 Antibody
SKU: 75-067