Anti-VAPA/B Antibody (N479/107)

Name: Anti-VAPA/B Antibody
Brand: NeuroMab
SKU: 75-496
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

1 Citation

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N479/107

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Vapa Vap33

Molecular Weight

30 kDa

Go to Full Product Details

Immunoblot against extracts of COS cells transiently transfected with GFP-tagged VAPA, VAPB or untagged Kv2.1 plasmid probed with N479/107 (left) or N86/8 (right) TC supe..

Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-VAPA/B Antibody

Product Details

Target

VAPA/B

Target Description

VAPA and VAPB are members of the VAMP-associated protein family (VAP) (aka vesicle-associated membrane proteins) which are abundant scaffolding proteins predominantly localized to the endoplasmic reticulum (ER). VAPs have recently been shown to interact with Kv2.1 and Kv2.2 channels forming junctions to link the ER to the plasma membrane (Johnson B. et al., 2018).

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N479/107

Isotype

IgG2b

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Vapa Vap33

Molecular Weight

30 kDa

Antigen

Fusion protein amino acids 1-219 (N-terminus) of rat VAPA (accession number Q9Z270) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2722711

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

VAPA (Vesicle-associated membrane protein-associated protein A) (VAMP-associated protein A) (33 kDa VAMPassociatedprotein) (VAMP-A) (VAP-33)

UniProt Details

UniProt (Human): Q9P0L0
UniProt (Immunogen Species): Q9Z270

Product Specific References for Applications and Species

Immunohistochemistry: Rat

Immunohistochemistry: Rat
PMID	Dilution	Publication
33449375	1:250	Deardoff, A.S., et al. 2021. Location, location, location: the organization and roles of potassium channels in mammalian motoneurons. Journal of Physiology, 1391-1420.

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Anti-VAPA/B Antibody (N479/107)

Available Conjugates

Anti-VAPA/B Antibody
SKU: 75-496

Bulk Order Anti-VAPA/B Antibody

Product Details

Product Specific References for Applications and Species

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Anti-VAPA/B Antibody (N479/107)

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Anti-VAPA/B Antibody SKU: 75-496

Bulk Order Anti-VAPA/B Antibody

Product Details

Product Specific References for Applications and Species

Anti-VAPA/B Antibody
SKU: 75-496