Transfected cell immunoblot: extracts of COS cells transiently transfected with Myc- tagged Uncx and untagged Kv2.1 plasmids and probed with N155/9 (left) and 19E10 (right) TC supes.
Homeobox protein unc-4 homolog is encoded by the gene UNCX. UNCX functions as a transcription factor in somitogenesis and neurogenesis. UNCX is required for the maintenance and differentiation of specific elements of the axial skeleton. UNCX is expressed in the eye, brain and kidney. Diseases associated with UNCX include Autosomal Recessive Spondylocostal Dysostosis.
Fusion protein amino acids 191-530 (C-terminus) of mouse Uncx (also known as UNC4 protein, Uncx4.1, Transcriptional control factor, Paired-type homeodomain transcription factor and PHD1, accession number O75164); Rat: 97% identity (330/340 amino acids identical); Human: 82% identity (287/350 amino acids identical)
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These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Homeobox protein unc-4 homolog (Homeobox protein Uncx4.1)