Anti-Tyrosine Hydroxylase Antibody (Purified) (LNC1)

Name: Anti-Tyrosine Hydroxylase Antibody (Purified)
Brand: Antibodies Incorporated
SKU: 77-700
Price: 374.0 USD
Availability: InStock

98 Citations

Our Anti-Tyrosine Hydroxylase (TH) mouse monoclonal primary antibody from Antibodies Incorporated is produced in-house from hybridoma clone LNC1. It detects chicken, frog, human, lizard, monkey, mouse, rat, vole, and zebrafish Tyrosine Hydroxylase (TH), and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Double-labeled fluorescence immunohistochemistry of human midbrain dopamine neurons stained green with LNC1 and red with PitX.

Western Blot of HEK293 cells transfected to express human Tyrosine Hydroxylase isoform 2 and Green Fluorescent Protein demonstrates the specificity of mouse monoclonal antibody LNC1 to tyrosine hydroxylase protein.

LNC1 anti-TH monoclonal antibody was used at 2.5ug/mL to stain endogenous tyrosine hydroxylase in rat brain lysate.

Mouse brain midbrain dopamine neurons in the substantia nigra double-labeled with LNC1 for tyrosine hydroxylase (TH, red and cytoplasmic) and a rabbit antibody to Nuclear Factor Y subunit A (NFYA, green and primarily nuclear).

Double-labeled fluorescence immunohistochemistry of human midbrain dopamine neurons stained green with LNC1 and red with PitX.

Species Reactivity

Chicken, Human, Lizard, Mouse, Non-Human Primate, Rat, Vole, Xenopus, Zebrafish

Applications

ICC, IHC, IP, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

Go to Full Product Details

Data Sheet

Trial Size

SKU: 77-700

Volume: 100 µL

Variant

Price:

$374.00

Quantity:

Product Details

Target

Tyrosine Hydroxylase (TH)

Target Description

TH is the rate-limiting enzyme in the synthesis of the catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine and is responsible for converting L-tyrosine to L-dopa. Synthesis of catecholamines is regulated by the interaction of TH with its’ cofactor, tetrahydrobiopterin (BH4) and the substrates L-tyrosine and molecular oxygen. In humans four TH mRNA splice variants (hTH1-hTH4) have been isolated while subprimate species rely on a single form of TH. It is known that the hTH1-hTH4 variants are identical in their catalytic domain but differ in their N-terminal regulatory domains. Importantly, LNC1 reacts with the catalytic domain of TH and thus with all four isoforms of human TH. The role of TH in the synthesis of catecholamine neurotransmitters suggests a connection between the enzyme and a number of neuropathogenic diseases characterized by irregular catecholamine levels, such as Parkinson's disease, schizophrenia, and dystonia, as well as a variety of cardiovascular diseases.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

LNC1

Isotype

IgG1

Applications

ICC, IHC, IP, WB

Host Species

Mouse

Gene Name

TH TYH EC 1.14.16.2

Molecular Weight

59-63 kDa

Antigen

Tyrosine Hydroxylase purified from PC12 cells

Species Reactivity

Chicken, Human, Lizard, Mouse, Non-Human Primate, Rat, Vole, Xenopus, Zebrafish

Antibody Registry ID

AB_2940724

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Recognizes an epitope outside of the regulatory N-terminus. Recognizes a protein of approximately 59-61 kDa by Western blot. Does not react with the following on Western Blots: purified dopamine-beta-hydroxylase, phenylalanine hydroxylase, trytophan hydroxylase, dehydropteridine reductase, sepiapterin reductase or phenethanolamine-N-methyl transferase (PNMT). Identifies a single ~60 kDa band on Western Blots of HeLa cells transfected to express human tyrosine hydroxylase.

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe rat brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Tyrosine 3-monooxygenase

UniProt Details

UniProt (Human): P07101
UniProt (Immunogen Species): P07101

Sharaf A, Rahhal B, Spittau B, Roussa E. Localization of reelin signaling pathway components in murine midbrain and striatum.. Cell and tissue research 359 393-407 2015.
Chand AN, Galliano E, Chesters RA, Grubb MS. A distinct subtype of dopaminergic interneuron displays inverted structural plasticity at the axon initial segment.. The Journal of neuroscience : the official journal of the Society for Neuroscience 35 1573-90 2015.
Zhang S, Qi J, Li X, Wang HL, Britt JP, Hoffman AF, Bonci A, Lupica CR, Morales M. Dopaminergic and glutamatergic microdomains in a subset of rodent mesoaccumbens axons.. Nature neuroscience 18 386-92 2015.
Root DH, Hoffman AF, Good CH, Zhang S, Gigante E, Lupica CR, Morales M. Norepinephrine activates dopamine D4 receptors in the rat lateral habenula.. The Journal of neuroscience : the official journal of the Society for Neuroscience 35 3460-9 2015.
Uemura N, Koike M, Ansai S, Kinoshita M, Ishikawa-Fujiwara T, Matsui H, Naruse K, Sakamoto N, Uchiyama Y, Todo T, Takeda S, Yamakado H, Takahashi R. Viable neuronopathic Gaucher disease model in Medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein.. PLoS genetics 11 e1005065 2015.
Forlano PM, Ghahramani ZN, Monestime CM, Kurochkin P, Chernenko A, Milkis D. Catecholaminergic innervation of central and peripheral auditory circuitry varies with reproductive state in female midshipman fish, Porichthys notatus.. PloS one 10 e0121914 2015.
Schreglmann SR, Regensburger M, Rockenstein E, Masliah E, Xiang W, Winkler J, Winner B. The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice.. PloS one 10 e0126261 2015.
Zharikov AD, Cannon JR, Tapias V, Bai Q, Horowitz MP, Shah V, El Ayadi A, Hastings TG, Greenamyre JT, Burton EA. shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model.. The Journal of clinical investigation 125 2721-35 2015.
Van Rompuy AS, Oliveras-Salvá M, Van der Perren A, Corti O, Van den Haute C, Baekelandt V. Nigral overexpression of alpha-synuclein in the absence of parkin enhances alpha-synuclein phosphorylation but does not modulate dopaminergic neurodegeneration.. Molecular neurodegeneration 10 23 2015.
Bourdenx M, Dovero S, Engeln M, Bido S, Bastide MF, Dutheil N, Vollenweider I, Baud L, Piron C, Grouthier V, Boraud T, Porras G, Li Q, Baekelandt V, Scheller D, Michel A, Fernagut PO, Georges F, Courtine G, Bezard E, Dehay B. Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression.. Acta neuropathologica communications 3 46 2015.
Hitora-Imamura N, Miura Y, Teshirogi C, Ikegaya Y, Matsuki N, Nomura H. Prefrontal dopamine regulates fear reinstatement through the downregulation of extinction circuits.. eLife 4 2015.
Jiang YH, Jiang P, Yang JL, Ma DF, Lin HQ, Su WG, Wang Z, Li X. Cardiac Dysregulation and Myocardial Injury in a 6-Hydroxydopamine-Induced Rat Model of Sympathetic Denervation.. PloS one 10 e0133971 2015.
Dearborn JT, Harmon SK, Fowler SC, O'Malley KL, Taylor GT, Sands MS, Wozniak DF. Comprehensive functional characterization of murine infantile Batten disease including Parkinson-like behavior and dopaminergic markers.. Scientific reports 5 12752 2015.
Greferath U, Anderson EE, Jobling AI, Vessey KA, Martinez G, de Iongh RU, Kalloniatis M, Fletcher EL. Inner retinal change in a novel rd1-FTL mouse model of retinal degeneration.. Frontiers in cellular neuroscience 9 293 2015.
Sahin G, Thompson LH, Lavisse S, Ozgur M, Rbah-Vidal L, Dollé F, Hantraye P, Kirik D. Differential dopamine receptor occupancy underlies L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.. PloS one 9 e90759 2014.
Liu HF, Lu S, Ho PW, Tse HM, Pang SY, Kung MH, Ho JW, Ramsden DB, Zhou ZJ, Ho SL. LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity.. Annals of clinical and translational neurology 1 199-208 2014.
Qi J, Zhang S, Wang HL, Wang H, de Jesus Aceves Buendia J, Hoffman AF, Lupica CR, Seal RP, Morales M. A glutamatergic reward input from the dorsal raphe to ventral tegmental area dopamine neurons.. Nature communications 5 5390 2014.
Simpson EH, Morud J, Winiger V, Biezonski D, Zhu JP, Bach ME, Malleret G, Polan HJ, Ng-Evans S, Phillips PE, Kellendonk C, Kandel ER. Genetic variation in COMT activity impacts learning and dopamine release capacity in the striatum.. Learning & memory (Cold Spring Harbor, N.Y.) 21 205-14 2014.
Bifsha P, Yang J, Fisher RA, Drouin J. Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra.. PLoS genetics 10 e1004863 2014.
Choi DH, Kim JH, Seo JH, Lee J, Choi WS, Kim YS. Matrix metalloproteinase-3 causes dopaminergic neuronal death through Nox1-regenerated oxidative stress.. PloS one 9 e115954 2014.
Van Kampen JM, Baranowski D, Kay DG. Progranulin gene delivery protects dopaminergic neurons in a mouse model of Parkinson's disease.. PloS one 9 e97032 2014.
Miyoshi K, Kasahara K, Murakami S, Takeshima M, Kumamoto N, Sato A, Miyazaki I, Matsuzaki S, Sasaoka T, Katayama T, Asanuma M. Lack of dopaminergic inputs elongates the primary cilia of striatal neurons.. PloS one 9 e97918 2014.
Lopez JP, Lim R, Cruceanu C, Crapper L, Fasano C, Labonte B, Maussion G, Yang JP, Yerko V, Vigneault E, El Mestikawy S, Mechawar N, Pavlidis P, Turecki G. miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment.. Nature medicine 20 764-8 2014.
Montavon G, Jauquier N, Coulon A, Peuchmaur M, Flahaut M, Bourloud KB, Yan P, Delattre O, Sommer L, Joseph JM, Janoueix-Lerosey I, Gross N, Mühlethaler-Mottet A. Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells.. Oncotarget 5 4452-66 2014.
Shivers KY, Nikolopoulou A, Machlovi SI, Vallabhajosula S, Figueiredo-Pereira ME. PACAP27 prevents Parkinson-like neuronal loss and motor deficits but not microglia activation induced by prostaglandin J2.. Biochimica et biophysica acta 1842 1707-19 2014.
Lotan D, Cunningham M, Joel D. Antibiotic treatment attenuates behavioral and neurochemical changes induced by exposure of rats to group a streptococcal antigen.. PloS one 9 e101257 2014.
Lute B, Jou W, Lateef DM, Goldgof M, Xiao C, Piñol RA, Kravitz AV, Miller NR, Huang YG, Girardet C, Butler AA, Gavrilova O, Reitman ML. Biphasic effect of melanocortin agonists on metabolic rate and body temperature.. Cell metabolism 20 333-45 2014.
Tapias V, Cannon JR, Greenamyre JT. Pomegranate juice exacerbates oxidative stress and nigrostriatal degeneration in Parkinson's disease.. Neurobiology of aging 35 1162-76 2014.
Bai Q, Parris RS, Burton EA. Different mechanisms regulate expression of zebrafish myelin protein zero (P0) in myelinating oligodendrocytes and its induction following axonal injury.. The Journal of biological chemistry 289 24114-28 2014.
Trabalza A, Eleftheriadou I, Sgourou A, Liao TY, Patsali P, Lee H, Mazarakis ND. Enhanced central nervous system transduction with lentiviral vectors pseudotyped with RVG/HIV-1gp41 chimeric envelope glycoproteins.. Journal of virology 88 2877-90 2014.
Pinheiro PS, Jansen AM, de Wit H, Tawfik B, Madsen KL, Verhage M, Gether U, Sørensen JB. The BAR domain protein PICK1 controls vesicle number and size in adrenal chromaffin cells.. The Journal of neuroscience : the official journal of the Society for Neuroscience 34 10688-700 2014.
Sousa JB, Vieira-Rocha MS, Sá C, Ferreirinha F, Correia-de-Sá P, Fresco P, Diniz C. Lack of endogenous adenosine tonus on sympathetic neurotransmission in spontaneously hypertensive rat mesenteric artery.. PloS one 9 e105540 2014.
Contreras GA, Lee YH, Mottillo EP, Granneman JG. Inducible brown adipocytes in subcutaneous inguinal white fat: the role of continuous sympathetic stimulation.. American journal of physiology. Endocrinology and metabolism 307 E793-9 2014.
Nomura S, Bouhadana M, Morel C, Faure P, Cauli B, Lambolez B, Hepp R. Noradrenalin and dopamine receptors both control cAMP-PKA signaling throughout the cerebral cortex.. Frontiers in cellular neuroscience 8 247 2014.
Fifel K, Vezoli J, Dzahini K, Claustrat B, Leviel V, Kennedy H, Procyk E, Dkhissi-Benyahya O, Gronfier C, Cooper HM. Alteration of daily and circadian rhythms following dopamine depletion in MPTP treated non-human primates.. PloS one 9 e86240 2014.
Masuda C, Takeuchi S, J Bisem N, R Vincent S, Tooyama I. Immunohistochemical Localization of an Isoform of TRK-Fused Gene-Like Protein in the Rat Retina.. Acta histochemica et cytochemica 47 75-83 2014.
Ray B, Chopra N, Long JM, Lahiri DK. Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research.. Molecular brain 7 63 2014.
Orts-Del'Immagine A, Kastner A, Tillement V, Tardivel C, Trouslard J, Wanaverbecq N. Morphology, distribution and phenotype of polycystin kidney disease 2-like 1-positive cerebrospinal fluid contacting neurons in the brainstem of adult mice.. PloS one 9 e87748 2014.
Bakthavatsalam S, Das Sharma S, Sonawane M, Thirumalai V, Datta A. A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity.. Disease models & mechanisms 7 1239-51 2014.
Chuhma N, Mingote S, Moore H, Rayport S. Dopamine neurons control striatal cholinergic neurons via regionally heterogeneous dopamine and glutamate signaling.. Neuron 81 901-12 2014.
Berthet A, Margolis EB, Zhang J, Hsieh I, Zhang J, Hnasko TS, Ahmad J, Edwards RH, Sesaki H, Huang EJ, Nakamura K. Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons.. The Journal of neuroscience : the official journal of the Society for Neuroscience 34 14304-17 2014.
Farrell KF, Krishnamachari S, Villanueva E, Lou H, Alerte TN, Peet E, Drolet RE, Perez RG. Non-motor parkinsonian pathology in aging A53T α-synuclein mice is associated with progressive synucleinopathy and altered enzymatic function.. Journal of neurochemistry 128 536-46 2014.
Good CH, Wang H, Chen YH, Mejias-Aponte CA, Hoffman AF, Lupica CR. Dopamine D4 receptor excitation of lateral habenula neurons via multiple cellular mechanisms.. The Journal of neuroscience : the official journal of the Society for Neuroscience 33 16853-64 2013.
Achim K, Peltopuro P, Lahti L, Tsai HH, Zachariah A, Astrand M, Salminen M, Rowitch D, Partanen J. The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors.. Biology open 2 990-7 2013.
Zhang N, Favazza TL, Baglieri AM, Benador IY, Noonan ER, Fulton AB, Hansen RM, Iuvone PM, Akula JD. The rat with oxygen-induced retinopathy is myopic with low retinal dopamine.. Investigative ophthalmology & visual science 54 8275-84 2013.
Oliveras-Salvá M, Van der Perren A, Casadei N, Stroobants S, Nuber S, D'Hooge R, Van den Haute C, Baekelandt V. rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration.. Molecular neurodegeneration 8 44 2013.
Gombash SE, Manfredsson FP, Kemp CJ, Kuhn NC, Fleming SM, Egan AE, Grant LM, Ciucci MR, MacKeigan JP, Sortwell CE. Morphological and behavioral impact of AAV2/5-mediated overexpression of human wildtype alpha-synuclein in the rat nigrostriatal system.. PloS one 8 e81426 2013.
Stephenson-Jones M, Kardamakis AA, Robertson B, Grillner S. Independent circuits in the basal ganglia for the evaluation and selection of actions.. Proceedings of the National Academy of Sciences of the United States of America 110 E3670-9 2013.
Orenstein SJ, Kuo SH, Tasset I, Arias E, Koga H, Fernandez-Carasa I, Cortes E, Honig LS, Dauer W, Consiglio A, Raya A, Sulzer D, Cuervo AM. Interplay of LRRK2 with chaperone-mediated autophagy.. Nature neuroscience 16 394-406 2013.
Chaudhry Zohara L and Ahmed Bushra Y. Caspase-2 and caspase-8 trigger caspase-3 activation following 6-OHDA-induced stress in human dopaminergic neurons differentiated from ReNVM stem cells.. Neurol. Res., 35: 435-40 (2013) 2013.
Muto A, Taylor MR, Suzawa M, Korenbrot JI, Baier H. Glucocorticoid receptor activity regulates light adaptation in the zebrafish retina.. Frontiers in neural circuits 7 145 2013.
Bathina CS, Rajulapati A, Franzke M, Yamamoto K, Cunningham JT, Mifflin S. Knockdown of tyrosine hydroxylase in the nucleus of the solitary tract reduces elevated blood pressure during chronic intermittent hypoxia.. American journal of physiology. Regulatory, integrative and comparative physiology 305 R1031-9 2013.
Tapias V, Greenamyre JT, Watkins SC. Automated imaging system for fast quantitation of neurons, cell morphology and neurite morphometry in vivo and in vitro.. Neurobiology of disease 54 158-68 2013.
Bäck S, Peränen J, Galli E, Pulkkila P, Lonka-Nevalaita L, Tamminen T, Voutilainen MH, Raasmaja A, Saarma M, Männistö PT, Tuominen RK. Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease.. Brain and behavior 3 75-88 2013.
Brown AL, Day TA, Dayas CV, Smith DW. Purity and enrichment of laser-microdissected midbrain dopamine neurons.. BioMed research international 2013 747938 2013.
Zahm DS, Parsley KP, Schwartz ZM, Cheng AY. On lateral septum-like characteristics of outputs from the accumbal hedonic "hotspot" of Peciña and Berridge with commentary on the transitional nature of basal forebrain "boundaries".. The Journal of comparative neurology 521 50-68 2013.
Takase K, Oda S, Kuroda M, Funato H. Monoaminergic and neuropeptidergic neurons have distinct expression profiles of histone deacetylases.. PloS one 8 e58473 2013.
Ulusoy A, Rusconi R, Pérez-Revuelta BI, Musgrove RE, Helwig M, Winzen-Reichert B, Di Monte DA. Caudo-rostral brain spreading of α-synuclein through vagal connections.. EMBO molecular medicine 5 1051-9 2013.
Bolding MS, Reid MA, Avsar KB, Roberts RC, Gamlin PD, Gawne TJ, White DM, den Hollander JA, Lahti AC. Magnetic transfer contrast accurately localizes substantia nigra confirmed by histology.. Biological psychiatry 73 289-94 2013.
de Almeida Chaves Rodrigues AF, de Lima IL, Bergamaschi CT, Campos RR, Hirata AE, Schoorlemmer GH, Gomes GN. Increased renal sympathetic nerve activity leads to hypertension and renal dysfunction in offspring from diabetic mothers.. American journal of physiology. Renal physiology 304 F189-97 2013.
Feng L, Zhao Y, Yoshida M, Chen H, Yang JF, Kim TS, Cang J, Troy JB, Liu X. Sustained ocular hypertension induces dendritic degeneration of mouse retinal ganglion cells that depends on cell type and location.. Investigative ophthalmology & visual science 54 1106-17 2013.
Elsworth JD, Jentsch JD, Vandevoort CA, Roth RH, Jr DE, Leranth C. Prenatal exposure to bisphenol A impacts midbrain dopamine neurons and hippocampal spine synapses in non-human primates.. Neurotoxicology 35 113-20 2013.
Ohtsuka N, Badurek S, Busslinger M, Benes FM, Minichiello L, Rudolph U. GABAergic neurons regulate lateral ventricular development via transcription factor Pax5.. Genesis (New York, N.Y. : 2000) 51 234-45 2013.
Bäck S, Raki M, Tuominen RK, Raasmaja A, Bergström K, Männistö PT. High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats.. EJNMMI research 3 46 2013.
Cannon JR, Geghman KD, Tapias V, Sew T, Dail MK, Li C, Greenamyre JT. Expression of human E46K-mutated α-synuclein in BAC-transgenic rats replicates early-stage Parkinson's disease features and enhances vulnerability to mitochondrial impairment.. Experimental neurology 240 44-56 2013.
Bergami M, Vignoli B, Motori E, Pifferi S, Zuccaro E, Menini A, Canossa M. TrkB signaling directs the incorporation of newly generated periglomerular cells in the adult olfactory bulb.. The Journal of neuroscience : the official journal of the Society for Neuroscience 33 11464-78 2013.
Garcia-Reitboeck P, Anichtchik O, Dalley JW, Ninkina N, Tofaris GK, Buchman VL, Spillantini MG. Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra.. Experimental neurology 248 541-5 2013.
Matthews GA, Patel R, Walsh A, Davies O, Martínez-Ricós J, Brennan PA. Mating increases neuronal tyrosine hydroxylase expression and selectively gates transmission of male chemosensory information in female mice.. PloS one 8 e69943 2013.
Kouki KatoJun WakaiHideki MatsudaTatsumi KusakabeYoshio Yamamoto. Increased total volume and dopamine β-hydroxylase immunoreactivity of carotid body in spontaneously hypertensive rats.. Autonomic neuroscience : basic & clinical 169 2012.
Achim K, Peltopuro P, Lahti L, Li J, Salminen M, Partanen J. Distinct developmental origins and regulatory mechanisms for GABAergic neurons associated with dopaminergic nuclei in the ventral mesodiencephalic region.. Development (Cambridge, England) 139 2360-70 2012.
Gallagher SK, Anglen JN, Mower JM, Vigh J. Dopaminergic amacrine cells express opioid receptors in the mouse retina.. Visual neuroscience 29 203-9 2012.
Mandemakers W, Snellinx A, O'Neill MJ, de Strooper B. LRRK2 expression is enriched in the striosomal compartment of mouse striatum.. Neurobiology of disease 48 582-93 2012.
Y-C ChenM SundvikS RozovM PriyadarshiniP Panula. MANF regulates dopaminergic neuron development in larval zebrafish.. Developmental biology 370 2012.
K Sakai. Discharge properties of presumed cholinergic and noncholinergic laterodorsal tegmental neurons related to cortical activation in non-anesthetized mice.. Neuroscience 224 2012.
Filipe C MatheusAderbal S AguiarAdalberto A CastroJardel G VillarinhoJuliano FerreiraCl FigueiredoRoger WalzAdair R S SantosCarla I TascaRui D S Prediger. Neuroprotective effects of agmatine in mice infused with a single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).. Behavioural brain research 235 2012.
Virolainen SM, Achim K, Peltopuro P, Salminen M, Partanen J. Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres.. Development (Cambridge, England) 139 3795-805 2012.
Peng C, Li N, Ng YK, Zhang J, Meier F, Theis FJ, Merkenschlager M, Chen W, Wurst W, Prakash N. A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation.. The Journal of neuroscience : the official journal of the Society for Neuroscience 32 13292-308 2012.
Vázquez-Roque RA Ramos B Tecuatl C Juárez I Adame A de la Cruz F Zamudio S Mena R Rockenstein E Masliah E Flores G. Chronic administration of the neurotrophic agent cerebrolysin ameliorates the behavioral and morphological changes induced by neonatal ventral hippocampus lesion in a rat model of schizophrenia.. Journal of neuroscience research 90 288-306. doi 2012.
Schärer YP, Shum J, Moressis A, Friedrich RW. Dopaminergic modulation of synaptic transmission and neuronal activity patterns in the zebrafish homolog of olfactory cortex.. Frontiers in neural circuits 6 76 2012.
Grant WF, Nicol LE, Thorn SR, Grove KL, Friedman JE, Marks DL. Perinatal exposure to a high-fat diet is associated with reduced hepatic sympathetic innervation in one-year old male Japanese macaques.. PloS one 7 e48119 2012.
Trabalza A et al.. Venezuelan equine encephalitis virus glycoprotein pseudotyping confers neurotropism to lentiviral vectors.. Gene Ther., (2012) 2012.
Eman I AhmedKatharine V NorthcuttJoseph S Lonstein. L-amino acid decarboxylase- and tyrosine hydroxylase-immunoreactive cells in the extended olfactory amygdala and elsewhere in the adult prairie vole brain.. Journal of chemical neuroanatomy 43 2012.
Gorbatyuk MS, Shabashvili A, Chen W, Meyers C, Sullivan LF, Salganik M, Lin JH, Lewin AS, Muzyczka N, Gorbatyuk OS. Glucose regulated protein 78 diminishes α-synuclein neurotoxicity in a rat model of Parkinson disease.. Molecular therapy : the journal of the American Society of Gene Therapy 20 1327-37 2012.
Tanaka K, Furuyashiki T, Kitaoka S, Senzai Y, Imoto Y, Segi-Nishida E, Deguchi Y, Breyer RM, Breyer MD, Narumiya S. Prostaglandin E2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice.. The Journal of neuroscience : the official journal of the Society for Neuroscience 32 4319-29 2012.
Ohuchi H, Yamashita T, Tomonari S, Fujita-Yanagibayashi S, Sakai K, Noji S, Shichida Y. A non-mammalian type opsin 5 functions dually in the photoreceptive and non-photoreceptive organs of birds.. PloS one 7 e31534 2012.
Sherry DM, Kanan Y, Hamilton R, Hoffhines A, Arbogast KL, Fliesler SJ, Naash MI, Moore KL, Al-Ubaidi MR. Differential developmental deficits in retinal function in the absence of either protein tyrosine sulfotransferase-1 or -2.. PloS one 7 e39702 2012.
Arime Y, Kasahara Y, Hall FS, Uhl GR, Sora I. Cortico-subcortical neuromodulation involved in the amelioration of prepulse inhibition deficits in dopamine transporter knockout mice.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 37 2522-30 2012.
Heaton JH, Wood MA, Kim AC, Lima LO, Barlaskar FM, Almeida MQ, Fragoso MC, Kuick R, Lerario AM, Simon DP, Soares IC, Starnes E, Thomas DG, Latronico AC, Giordano TJ, Hammer GD. Progression to adrenocortical tumorigenesis in mice and humans through insulin-like growth factor 2 and β-catenin.. The American journal of pathology 181 1017-33 2012.
Lui NP, Chen LW, Yung WH, Chan YS, Yung KK. Endogenous repair by the activation of cell survival signalling cascades during the early stages of rat Parkinsonism.. PloS one 7 e51294 2012.
Leung TC, Lui CN, Chen LW, Yung WH, Chan YS, Yung KK. Ceftriaxone ameliorates motor deficits and protects dopaminergic neurons in 6-hydroxydopamine-lesioned rats.. ACS chemical neuroscience 3 22-30 2012.
Purves-Tyson TD, Handelsman DJ, Double KL, Owens SJ, Bustamante S, Weickert CS. Testosterone regulation of sex steroid-related mRNAs and dopamine-related mRNAs in adolescent male rat substantia nigra.. BMC neuroscience 13 95 2012.
Mitrano DA, Schroeder JP, Smith Y, Cortright JJ, Bubula N, Vezina P, Weinshenker D. α-1 Adrenergic receptors are localized on presynaptic elements in the nucleus accumbens and regulate mesolimbic dopamine transmission.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 37 2161-72 2012.
Miller RL, Knuepfer MM, Wang MH, Denny GO, Gray PA, Loewy AD. Fos-activation of FoxP2 and Lmx1b neurons in the parabrachial nucleus evoked by hypotension and hypertension in conscious rats.. Neuroscience 218 110-25 2012.
McIntyre JC, Davis EE, Joiner A, Williams CL, Tsai IC, Jenkins PM, McEwen DP, Zhang L, Escobado J, Thomas S, Szymanska K, Johnson CA, Beales PL, Green ED, Mullikin JC, , Sabo A, Muzny DM, Gibbs RA, Attié-Bitach T, Yoder BK, Reed RR, Katsanis N, Martens JR. Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model.. Nature medicine 18 1423-8 2012.
Henry MA, Luo S, Levinson SR. Unmyelinated nerve fibers in the human dental pulp express markers for myelinated fibers and show sodium channel accumulations.. BMC neuroscience 13 29 2012.
Liu J, Githinji J, Mclaughlin B, Wilczek K, Nolta J. Role of miRNAs in neuronal differentiation from human embryonic stem cell-derived neural stem cells.. Stem cell reviews 8 1129-37 2012.
Fortin GM, Bourque MJ, Mendez JA, Leo D, Nordenankar K, Birgner C, Arvidsson E, Rymar VV, Bérubé-Carrière N, Claveau AM, Descarries L, Sadikot AF, Wallén-Mackenzie Å, Trudeau LÉ. Glutamate corelease promotes growth and survival of midbrain dopamine neurons.. The Journal of neuroscience : the official journal of the Society for Neuroscience 32 17477-91 2012.
Gombash SE, Lipton JW, Collier TJ, Madhavan L, Steece-Collier K, Cole-Strauss A, Terpstra BT, Spieles-Engemann AL, Daley BF, Wohlgenant SL, Thompson VB, Manfredsson FP, Mandel RJ, Sortwell CE. Striatal pleiotrophin overexpression provides functional and morphological neuroprotection in the 6-hydroxydopamine model.. Molecular therapy : the journal of the American Society of Gene Therapy 20 544-54 2012.

Recover password

Create my account

Anti-Tyrosine Hydroxylase Antibody (Purified) (LNC1)

SKU: 77-700

Product Details

Bulk Order Anti-Tyrosine Hydroxylase Antibody (Purified)

Related Products

Recently Viewed