Anti-Tumor necrosis factor receptor superfamily member 19 (TROY) Antibody

Name: Anti-Tumor necrosis factor receptor superfamily member 19 (TROY) Antibody
Brand: Biosensis
SKU: R-091-100
Price: 327.0 USD
Availability: InStock

Our Anti-Tumor necrosis factor receptor superfamily member 19 (TROY) rabbit polyclonal primary antibody detects mouse and rat Tumor necrosis factor receptor superfamily member 19 (TROY), and is whole serum. It is validated for use in IHC-Frozen.

The cryostat section of trigeminal ganglia was stained with the Rabbit antibody to mouse TROY (75-88): whole serum at the dilution of 1: 2000. Following incubation of the section with the primary antibody overnight and secondary antibody for 2 hours, the section was developed with diaminobenzidine substrate with nickel sulfate enhancement.

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Species Reactivity

Mouse, Rat

Applications

IHC

Host Species

Rabbit

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Data Sheet

SKU: R-091-100

Volume/Size: 100 µL

Variant

Price:

$327.00

Quantity:

Product Details

Target

Tumor necrosis factor receptor superfamily member 19 (TROY)

Scientific Background

FUNCTION: Can mediate activation of c-Jun and NF-kappa-B. May promote caspase-independent cell death. Isoform 2 and isoform 3 may act as decoy receptors. SUBUNIT: Associates with TRAF1, TRAF2, TRAF3 and TRAF5. SUBCELLULAR LOCATION: Isoform 1, isoform 3, isoform 4: Cell membrane; single-pass type I membrane protein (Probable). Isoform 2: Secreted protein (Probable). ALTERNATIVE PRODUCTS: 4 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Highly expressed in adult brain, and in embryos from day 11-17, but not earlier. Detected in embryonic brain and epithelium, and at lower levels in adult heart, lung and liver. In neonatal mice, mainly in hair follicles and neuron-like cells in the cerebellum, but not in the skin epidermis. Isoform 3 was found in embryonic day 17.5 skin but not in brain and liver. SIMILARITY: Contains 3 TNFR-Cys repeats.

Format

Whole serum

Clonality

Polyclonal

Isotype

Mixed

Applications

IHC

Host Species

Rabbit

Immunogen

A synthetic peptide (CRPHRF KEDWGFQK) as part of mouse TROY protein (aa: 75-88) conjugated to the immunogenic protein Blue Carrier Protein

Immunogen Species

Mouse

Species Reactivity

Mouse, Rat

Storage

Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Physical State

Lyophilized

Dilution Ranges

IHC: 1:500-1:2000

Conjugate

Unconjugated

Specificity

Specificity for TROY was confirmed by IHC. This antiserum is known to react with rat TROY. Reactivity with other species have not yet been tested.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

Tumor necrosis factor receptor superfamily member 19; TNFRSF19; Toxicity and JNK inducer; TRADE

UniProt ID

Q9JLL3

Shipping

25°C (ambient)

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Anti-Tumor necrosis factor receptor superfamily member 19 (TROY) Antibody

SKU: R-091-100

Product Details

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