Anti-TRIP8b (Exon 1b) Antibody FL650 Conjugate (N212A/34)

Name: Anti-TRIP8b (Exon 1b) Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-245-FL650
Price: 486.0 USD
Availability: InStock

Our mouse TRIP8b (exon 1b) FL650 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N212A/34. It detects human, mouse, and rat TRIP8b (exon 1b) and is purified by Protein A chromatography. Works in ICC.

Anti-TRIP8b (Exon 1b) Antibody FL650 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-245-FL650

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

TRIP8b (exon 1b)

Scientific Background

PEX5-related protein, Peroxisomal Biogenesis Factor 5 Like, TPR-containing Rab8b-interacting protein or TRIP8b is encoded by the gene Pex5l. It is a member of the peroxisomal targeting signal receptor family. TRIP8b is a cytoplasmic accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. TRIP8b interacts with the carboxyl-terminal region of HCN channels and regulates their cell-surface expression to the dendrites in many types of neurons. TRIP8b plays a role in regulation of HCN channel cyclic nucleotide kinetics. TRIP8b is expressed in the brain. Diseases associated with PEX5L include Rhizomelic Chondrodysplasia Punctata, Type 5 and Rhizomelic Chondrodysplasia Punctata, Type 2.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N212A/34

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Pex5l Pex2 Pex5r Pxr2

Molecular Weight

70 kDa

Immunogen

Fusion protein amino acids 1-205 (exon 1b, exon 2 and constant region) of mouse TRIP8b (accession number Q8C437-3) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939895

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Specific for exon 1b(does not react with TRIP8b isoforms containing exons 1a, 2 or 4)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

PEX5-related protein (PEX2-related protein) (PEX5-like protein) (Peroxin-5-related protein) (Tetratricopeptide repeat-containing Rab8b-interacting protein) (Pex5Rp) (TRIP8b)

UniProt ID

Q8C437-3

Shipping

Shipped on ice packs

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Anti-TRIP8b (Exon 1b) Antibody FL650 Conjugate (N212A/34)

SKU: 75-245-FL650

Product Details

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