Potassium two pore domain channel subfamily K member 18 is encoded by the gene KCNK18. KCNK18 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK18 is an outward rectifying potassium channel that produces rapidly activating outward rectifier K+ currents. KCNK18 is expressed in the brain, spinal cord, and testis. Diseases associated with KCNK18 include Migraine With or Without Aura 13 and Migraine with Aura.
Purified by Protein A chromatography
ICC, IHC, WB
Kcnk18 Tresk-2 Tresk2
Fusion protein amino acids 185-283 (intracellular loop) of mouse TRESK (accession number Q6VV64) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.